Original Articles

• Paeonol’s protective effects on H9C2 cells against hypoxia/ reoxygenation injury through the hypoxia-inducible factor 1-alpha/B-cell lymphoma-2/adenovirus E1B 19 kDa interacting protein 3 signaling pathway
• ZHAO Chengguo, YIN Meifang, ZHOU Menghan, QIN Shuzhi
• Abstract HTML PDF
  2026 Vol. 46 (4): 779-787. DOI: 10.19852/j.cnki.jtcm.2026.04.001

• Berberine alleviates alcoholic liver disease via activating intestinal nuclear receptor subfamily 1 group D member 1
• HUANG Yuwei, CAI Yuting, LI Zanjin, WU Zicong, GUO Lianxia, LIN Luomin, DONG Linlin, WU Baojian, DONG Dong
• Abstract HTML PDF
  2026 Vol. 46 (4): 788-797. DOI: 10.19852/j.cnki.jtcm.2026.04.002

• Baihe Dihuang decoction (百合地黄汤) activates cannabinoid type 2 receptor to regulate microglial polarization and alleviate anxiety-like behavior in chronic restraint stress mice
• LUO Qiaoyun, HAN Yuanshan, LIU Yang, TANG Lin, WANG Tianyu, WANG Yuhong, ZHAO Hongqing
• Abstract HTML PDF
  2026 Vol. 46 (4): 798-808. DOI: 10.19852/j.cnki.jtcm.2026.04.003

• Shaofu Zhuyu decoction (少腹逐瘀汤) can inhibit the progression of endometriosis fibrosis through the transforming growth factor-β1/ smads signaling pathway mediated by 5’ adenosine monophosphate-activated protein kinase
• LI Bingbing, DING Meiqi, CHEN Xiangying, LI Wenzhe, WEI Chao, YU Bin, MA Xiaona, SUN Xinhui
• Abstract HTML PDF
  2026 Vol. 46 (4): 809-820. DOI: 10.19852/j.cnki.jtcm.2026.04.004

• Yigongsan decoction (异功散) ameliorates anemia of chronic disease by attenuating mothers against decapentaplegic homolog-signal transducer and activator of transcription 3 interaction to regulate iron homeostasis
• ZHENG Qin, ZHU Xiaoqin, HU Jie, BU Jingyang, JI Yuting, JIANG Yiling, SHI Ling, ZHANG Aiping, WU Zhihao, XU Haitao, ZHANG Ruifeng, YANG Yang, LUO Meihong
• Abstract HTML PDF
  2026 Vol. 46 (4): 821-831. DOI: 10.19852/j.cnki.jtcm.2026.04.005

• Electroacupuncture enhances CD8+ T cells recruitment via modulating sympathetic nervous system to suppress tumor growth in mice bearing triple-negative breast cancer
• TIAN Yehong, ZHANG Qiaoli, ZHANG Rui, GAO Tao, LI Nanzhi, HUANG Jinchang, JIANG Xin, QIU Xiaowei
• Abstract HTML PDF
  2026 Vol. 46 (4): 832-843. DOI: 10.19852/j.cnki.jtcm.2026.04.006

• Regulatory effects and mechanisms of the acupuncture-induced complement component 1q on the high mobility group box 1 -receptor for advanced glycation end products-nuclear factor kappa-B pathway at Zusanli (ST36)
• KANG Xiaochun, WU Sinuo, LI Ningcen, XU Wenyue, XU Zhifang, Thong Yikchih, LI Peiyun, TU Shiwei, MA Ning, LI Yanwei, DOU Baomin, TAN Wenjun, GUO Jing, GUO Yi, PAN Xingfang, LÜ Zhongxi
• Abstract HTML PDF
  2026 Vol. 46 (4): 844-853. DOI: 10.19852/j.cnki.jtcm.20251201.001

• Therapeutic effect of Fuzheng Yixin decoction (扶正益心方) on cardiac insufficiency via the soluble guanylyl cyclase-cyclic guanosine monophosphate-protein kinase G pathway in a doxorubicin-induced dilated cardiomyopathy rat model
• SANG Xiuxiu, Lü Shuquan, WANG Feng, YANG Jing, WANG Qingguo, WANG Lixin
• Abstract HTML PDF
  2026 Vol. 46 (4): 854-863. DOI: 10.19852/j.cnki.jtcm.20260514.002

• Effects of Biling Weitong granules (荜铃胃痛颗粒) on gastrointestinal motility and gastrointestinal hormones levels in rats with functional dyspepsia
• GAO Lige, LI Xueyi, CHEN Feiyu, JIANG Changyu, LI Jiadi
• Abstract HTML PDF
  2026 Vol. 46 (4): 864-872. DOI: 10.19852/j.cnki.jtcm.2026.04.007

• Taohong Huazhuo decoction (桃红化浊汤) alleviates carbon tetrachloride-induced hepatic fibrosis in rats by inhibiting the nicotinamide adenine dinucleotide phosphate oxidase 4/nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 signaling pathway
• REN Yuan, CHEN Xiangni, SHI Lei, MAO Minghua, LI Shufang, YAO Jia, HAO Jianmei
• Abstract HTML PDF
  2026 Vol. 46 (4): 873-882. DOI: 10.19852/j.cnki.jtcm.2026.04.008

• Jianchang No. 1 (健肠1号) formula alleviates irritable bowel syndrome with diarrhea via improving gut microbiota and regulating toll-like receptors/nuclear factor-kappa B signaling pathway in bowel syndrome with diarrhea rats
• LIU Yutong, YANG Yan, XU Huiying, LI Lei, GE Fei, CHEN Meijuan
• Abstract HTML PDF
  2026 Vol. 46 (4): 883-893. DOI: 10.19852/j.cnki.jtcm.2026.04.009

• Electroacupuncture alleviates intestinal inflammation in rats with ulcerative colitis by regulating colonic cell autophagy and gut microbiota
• XU Huichao, HAO Jianheng, CHANG Boya, WANG Danni, LI Rangqian, CAO Yuxia, WANG Haijun, JI Laixi
• Abstract HTML PDF
  2026 Vol. 46 (4): 894-906. DOI: 10.19852/j.cnki.jtcm.2026.04.010

• Antihypertensive effect of acupuncture involve reshaping gut microbiota and alleviating gut inflammation in spontaneously hypertensive rats
• ZHENG Jie, DING Zhimin, CHEN Tingyu, LÜ Zhuan, ZHANG Lihong, LIU Yongtao, ZHANG Yasu, JIN Xiaoqin, WANG Xinyu, LIU Bin, FENG Xiaodong
• Abstract HTML PDF
  2026 Vol. 46 (4): 907-915. DOI: 10.19852/j.cnki.jtcm.2026.04.011

• Metabolomics and network pharmacology analysis of mechanisms underlying amelioration of tic disorders in rats by Jiawei Huangan Lipi decoction (加味缓肝理脾汤)
• CHEN Lijin, CHEN Linghui, WANG Chengrui, FANG Yijun, GAN Liping, HANG Jinyu
• Abstract HTML PDF
  2026 Vol. 46 (4): 916-926. DOI: 10.19852/j.cnki.jtcm.2026.04.012

• Mechanism of Yangxin Dawa Yimixike Mi Gao (养心达瓦) for myocardial ischemia/reperfusion injury: an integrative study of network pharmacology and in vivo and in vitro validation
• DONG Yuwei, RAN Qingzhi, ABDULLA Rahima, MAITINUER Maiwulanjiang, TIAN Fang, AISA Haji Akber
• Abstract HTML PDF
  2026 Vol. 46 (4): 927-940. DOI: 10.19852/j.cnki.jtcm.2026.04.013

• Efficacy and safety of Dingluo nasal drops (丁萝滴鼻剂) for the acute treatment of migraine: a pilot randomized trial
• YAO Yuning, AN Yuqiu, LIU Jiaojiao, DU Boxuan, CAO Kegang
• Abstract HTML PDF
  2026 Vol. 46 (4): 941-950. DOI: 10.19852/j.cnki.jtcm.2026.04.014

• Effect of Jinlong capsule (金龙胶囊) on the survival of patients with hepatocellular carcinoma: a propensity score matching study
• SHI Ke, ZHANG Yi, SUN lina, WANG Xianbo, FENG Ying
• Abstract HTML PDF
  2026 Vol. 46 (4): 951-960. DOI: 10.19852/j.cnki.jtcm.2026.04.015

• Efficacy and safety of Heshu Xiaoji pills (和枢消积丸) combined with standard treatment strategy in hepatitis B virus-related hepatocellular carcinoma: a single-center, open-label, prospective controlled, real-world cohort study
• ZHU Xiaoning, YIN Yue, KONG Yuan, PENG Mengyun, PENG Zhaoxuan, ZHENG Ding, WANG Xiaodong, HAN Yunwei, LI Bo, LIU Jurong, WANG Encheng, TIAN Zhen, PENG Qinghua, JIANG Yuanyuan, MI Shaoping, LIU Yong, PU Qingrong, GUO Yongcan, HE Qizhou, CHENG Chunxia, LI Linghua, JIA Hong, WANG Jing
• Abstract HTML PDF
  2026 Vol. 46 (4): 961-971. DOI: 10.19852/j.cnki.jtcm.2026.04.016

• Construction of a nomogram for anxiety and depression in patients with Sjögren’s syndrome by combining tongue and pulse characteristics: a cross-sectional study based on a prospective cohort
• SHAN Xueyan, HE Jiale, GUO Zilin, PANG Fengtao, LIU Ruihua, LIU Ying, JIANG Ping, JI Wei, YU Jing, ZHOU Xinyao, TANG Xiaopo
• Abstract HTML PDF
  2026 Vol. 46 (4): 972-981. DOI: 10.19852/j.cnki.jtcm.2026.04.017

• Traditional Chinese Medicine related factors of planned dialysis in chronic kidney disease stage 5 patients with type 2 diabetes mellitus: a multicenter cross-sectional study
• ZHANG Ruimin, LI Shuang, QU Yilun, WANG Qian, XIE Huidi, WANG Xiaolong, DUAN Shuwei, WU Jie, WANG Yong, DONG Zheyi, CHEN Xiangmei
• Abstract HTML PDF
  2026 Vol. 46 (4): 982-989. DOI: 10.19852/j.cnki.jtcm.2026.04.018

• Efficacy of Yishen Jiangzhuo granules (益肾降浊颗粒) in the treatment of chronic kidney disease stages 3-4: a retrospective cohort study
• RUAN Yaqing, RUAN Shiwei, YE Binhua, YU Yongxin, ZHENG Kailin
• Abstract HTML PDF
  2026 Vol. 46 (4): 990-999. DOI: 10.19852/j.cnki.jtcm.20260423.001

• Altered amino acids and acylcarnitines profile in infantile intrahepatic cholestasis liver disease: implication for Traditional Chinese Medicine syndrome differentiation
• QIU Yanyan, XIA Yu, LI Weiwei, YAN Suqi, PANG Yusheng
• Abstract HTML PDF
  2026 Vol. 46 (4): 1000-1008. DOI: 10.19852/j.cnki.jtcm.2026.04.019

• Effect of acupuncture and moxibustion combined with core stabilization training on the function of transverse abdominal muscle and pelvic floor muscle in women with postpartum pelvic pain
• SHI Ling, YANG Chengcheng, HUANG Li, DENG Linwen
• Abstract HTML PDF
  2026 Vol. 46 (4): 1009-1017. DOI: 10.19852/j.cnki.jtcm.2026.04.020

• Healing effects of Traditional Chinese Medicine plaster Heiyu Gao (黑玉膏) on refractory diabetic foot ulcers: a case series of ultra-elderly patients with surgical contraindications
• ZHANG Danyu, WU Chengxiang, WU Yu, GU Jingyu
• Abstract HTML PDF
  2026 Vol. 46 (4): 1018-1025. DOI: 10.19852/j.cnki.jtcm.2026.04.021

Review

• Intranasal essential oils in therapy: advances in clinical applications and delivery mechanisms
• LIANG Yong, GUAN Qiuyan, CHEN Yi, WU Wei, YANG Ming, TANG Fangrui, WANG Yawen, PAN Deng, HUANG Xiaoying, LI Huiting
• Abstract HTML PDF
  2026 Vol. 46 (4): 1026-1041. DOI: 10.19852/j.cnki.jtcm.2026.04.022