Acupoint catgut embedding for simple obesity in animal studies: a systematic review and Meta-analysis

doi:10.19852/j.cnki.jtcm.2023.05.002

Abstract

Abstract:

OBJECTIVE: To assess the efficacy of acupoint catgut embedding (ACE) for simple obesity in preclinical animal experiments.
METHODS: We searched the following 14 electronic databases: PubMed, Cochrane Library, EMBASE, Oriental Medicine Advanced Searching Integrated System, KoreaMed, Korean Studies Information Service System, Science-on, Research Information Sharing Service, Korea Citation Index, Korea Traditional Knowledge Portal, China Network Knowledge Infrastructure Database, Wanfang Database, Chinese Science and Technology Journal Database, and Chinese Biology Medicine Database, from inception to November 2021 without language limitation. The assessment was performed according to the guidelines of Animal Research: Reporting of in vivo experiments; and Meta-analysis was performed using Reviewer Manager 5.4.1 software.
RESULTS: Twenty-four studies involving 813 animals were selected. Meta-analysis showed that ACE was beneficial for weight control [n = 40, MD = -50.63, 95% CI (－57.59, －43.67), P < 0.000 01, I ²= 0%] and reduced the Lee index [n = 40, MD = －18.79, 95% CI (－20.01, －17.57), P < 0.000 01, I ²= 0%]. However, when efficacy of ACE was compared with that of manual acupuncture, electroacupuncture, or oilistat therapy, statistical difference was not observed between the two groups.
CONCLUSIONS: This systematic review suggests that ACE may be efficacious in treating obesity. Moreover, the analyses highlighted the necessity to perform well-designed, higher-quality experiments.

Key words: obesity, acupoint catgut embedding, animal study, Meta-analysis, systematic review

ZHAO HuiYan, JUN Purumea, LEE Chaewon, HAN Chang-Hyun. Acupoint catgut embedding for simple obesity in animal studies: a systematic review and Meta-analysis[J]. Journal of Traditional Chinese Medicine, 2023, 43(5): 860-867.

Figures/Tables 4

Figure 1 PRISMA 2020 flow diagram PRISMA: the Preferred Reporting Items for Systematic Reviews and Meta-Analyses; ACE: acupoint catgut embedding; CNKI: China Network Knowledge Infrastructure; KISS: Korean Studies Information Service System; KTKP: Korea Traditional Knowledge Portal; KCI: Korea Citation Index; VIP: Chinese science and technology journal database; SinoMed: Chinese Biology Medicine Database; RISS: Research Information Sharing Service; OASIS: Oriental Medicine Advanced Searching Integrated System.

Figure 2 Forest plot of Lee’s index ACE: acupoint catgut embedding; CI: confidence interval; SD: standard deviation.

Figure 3 Forest plot of body weight ACE: acupoint catgut embedding; CI: confidence interval; SD: standard deviation.

Figure 4 Publication bias of ACE vs model in body weight ACE: acupoint catgut embedding; MD: mean difference; SE: standard error.

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