Journal of Traditional Chinese Medicine ›› 2026, Vol. 46 ›› Issue (2): 501-508.DOI: 10.19852/j.cnki.jtcm.2026.02.021
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Tongue-coating microbiome as a predictor of solid tumors: an updated scoping review of clinical studies
LI Kexin1, YANG Jinzu2, XIAO Kunlin3, DUAN Shaojie4(
), XIAO Kunmin2()
- 1
Department of Traditional Chinese Medicine ,Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences Beijing 100730, China
2Department of Oncology ,Longhua Hospital, Shanghai University of Traditional Chinese Medicine Shanghai 200032, China
3Department of Emergency ,Zhongshan Hospital, Fudan University Shanghai 200030, China
4Department of Geriatrics ,Taizhou Central Hospital Taizhou 318000, China
-
Received:2024-12-25Accepted:2025-06-20Online:2026-04-15Published:2026-04-04 -
Contact:XIAO Kunmin, Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China. 20170931602@bucm.edu.cn; DUAN Shaojie, Department of Geriatrics, Taizhou Central Hospital, Taizhou 318000, China. 1782802171@qq.com; Telephone: +86-18801020572 -
About author:LI Kexin and YANG Jinzu are co-first authors and contributed equally to this work
Cite this article
LI Kexin, YANG Jinzu, XIAO Kunlin, DUAN Shaojie, XIAO Kunmin. Tongue-coating microbiome as a predictor of solid tumors: an updated scoping review of clinical studies[J]. Journal of Traditional Chinese Medicine, 2026, 46(2): 501-508.
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Figure 1 Flowchart of information progression in a scoping review
Figure 1 Flowchart of information progression in a scoping review
Figure 2 Tongue coating microbiome and metabolic dysregulation in gastric and colorectal tumor progression DCD: dermcidin; KRT2: keratin 2; KRT9: keratin 9; IFN-γ: interferon-γ; IL-1α: interleukin-1α; IL-5: interleukin-5; IL-10: interleukin-10; IL-12: interleukin-12; IL-17α: interleukin-17α; IL-23P40: interleukin-23 subunit p40; TNF-β: tumor necrosis factor-β; VEGF: vascular endothelial growth factor. Red arrows denote disease progression, and black arrows indicate the release of cytokine or lipid release.
Figure 2 Tongue coating microbiome and metabolic dysregulation in gastric and colorectal tumor progression DCD: dermcidin; KRT2: keratin 2; KRT9: keratin 9; IFN-γ: interferon-γ; IL-1α: interleukin-1α; IL-5: interleukin-5; IL-10: interleukin-10; IL-12: interleukin-12; IL-17α: interleukin-17α; IL-23P40: interleukin-23 subunit p40; TNF-β: tumor necrosis factor-β; VEGF: vascular endothelial growth factor. Red arrows denote disease progression, and black arrows indicate the release of cytokine or lipid release.
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