Journal of Traditional Chinese Medicine ›› 2024, Vol. 44 ›› Issue (6): 1268-1276.DOI: 10.19852/j.cnki.jtcm.2024.06.010
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A neural regulation mechanism of head electroacupuncture on brain network of patients with stroke related sleep disorders
ZHANG Boyang1, ZHOU Yang2, FENG Liyuan3, SUI Dan4, HE Lei5, TONG Dan6, WANG Ruoyu3, SUI Xue7, SONG Jing3, WANG Dongyan3(
)
- 1 Rehabilitation Department, Wuxi Hospital of Traditional Chinese Medicine, Wuxi 214000, China
2 Imaging Department, Harbin Medical University Cancer Hospital, Harbin 150000, China
3 Acu-Moxi Department III, the Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin 150000, China
4 Rehabilitation Department B, Second Hospital of Harbin, Harbin 150000, China
5 Acu-Moxi Department, Lianyungang Hospital of Traditional Chinese Medicine, Lianyungang 222000,China
6 Integrated TCM and Western Medicine Department, Suzhou Dushu lake hospital, Suzhou 215000, China
7 Internal Medicine Department, Zhaozhou Hospital of Traditional Chinese Medicine, Daqing 163000, China
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Received:2023-09-23Accepted:2024-01-10Online:2024-12-15Published:2024-11-12 -
Contact:WANG Dongyan -
About author:Prof. WANG Dongyan, Acu-Moxi Department Ⅲ, the Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Heilongjiang University of Traditional Chinese Medicine, Harbin 150000, China. doctwdy@163.com Telephone: +86-18646026767
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Supported by:National Natural Science Foundation of China Project: the Study of Central Mechanism of Electroacupuncture on Sishencong (EX-HN1) Improving Sleep Architecture and Neurocognitive Function Using Electroencephalogram-Functional Magnetic Resonance Imaging(81774426);Major Scientific Research Project of Wuxi Health Commission: Clinical Study of Intelligent Hand Rehabilitation Training System for Nerve Function Reconstruction of Patients with Hand Dysfunction after Cerebral Infarction(Z202121)
Cite this article
ZHANG Boyang, ZHOU Yang, FENG Liyuan, SUI Dan, HE Lei, TONG Dan, WANG Ruoyu, SUI Xue, SONG Jing, WANG Dongyan. A neural regulation mechanism of head electroacupuncture on brain network of patients with stroke related sleep disorders[J]. Journal of Traditional Chinese Medicine, 2024, 44(6): 1268-1276.
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Table 1 Scale scores comparing EA and SA groups before treatment ($\bar{x}±s$)
| Scale | SA group (n = 33) | EA group (n = 34) | F value | P value |
|---|---|---|---|---|
| PSQI | 13.7±2.0 | 14.6±2.7 | 2.87 | 0.095 |
| MoCA_B | 19.5±4.3 | 19.6±4.0 | 0.02 | 0.897 |
| SAS | 48.6±6.6 | 48.1±5.7 | 0.09 | 0.759 |
| SDS | 53.2±7.6 | 52.4±7.8 | 0.16 | 0.690 |
Table 1 Scale scores comparing EA and SA groups before treatment ($\bar{x}±s$)
| Scale | SA group (n = 33) | EA group (n = 34) | F value | P value |
|---|---|---|---|---|
| PSQI | 13.7±2.0 | 14.6±2.7 | 2.87 | 0.095 |
| MoCA_B | 19.5±4.3 | 19.6±4.0 | 0.02 | 0.897 |
| SAS | 48.6±6.6 | 48.1±5.7 | 0.09 | 0.759 |
| SDS | 53.2±7.6 | 52.4±7.8 | 0.16 | 0.690 |
Table 2 Scale scores comparing EA and SA groups after treatment
| Scale | SA group (n = 33) | EA group (n = 34) | F value | P value | ||
|---|---|---|---|---|---|---|
| MD | MD | |||||
| PSQI | 12.2±1.5 | －1.42 | 7.1±2.4 | －7.59 | 109.98 | <0.001 |
| MoCA_B | 21.9±2.8 | 2.36 | 26.1±2.2 | 6.41 | 45.79 | <0.001 |
| SAS | 45.2±5.3 | －3.37 | 40.0±5.1 | －8.14 | 16.79 | <0.001 |
| SDS | 50.0±6.4 | －3.19 | 43.8±5.8 | －8.60 | 17.09 | <0.001 |
Table 2 Scale scores comparing EA and SA groups after treatment
| Scale | SA group (n = 33) | EA group (n = 34) | F value | P value | ||
|---|---|---|---|---|---|---|
| MD | MD | |||||
| PSQI | 12.2±1.5 | －1.42 | 7.1±2.4 | －7.59 | 109.98 | <0.001 |
| MoCA_B | 21.9±2.8 | 2.36 | 26.1±2.2 | 6.41 | 45.79 | <0.001 |
| SAS | 45.2±5.3 | －3.37 | 40.0±5.1 | －8.14 | 16.79 | <0.001 |
| SDS | 50.0±6.4 | －3.19 | 43.8±5.8 | －8.60 | 17.09 | <0.001 |
Table 3 Scale scores comparing pre- and post-treatment within EA and SA groups
| Scales | Time | SA group (n = 33) | EA group (n = 34) | |||||
|---|---|---|---|---|---|---|---|---|
| F value | P value | F value | P value | |||||
| PSQI | Pre | 13.7±2.0 | 10.66 | 0.002 | 14.6±2.7 | 311.67 | <0.001 | |
| Post | 12.2±1.5 | 7.1±2.4 | ||||||
| MoCA_B | Pre | 19.5±4.3 | 26.88 | <0.001 | 19.6±4.0 | 203.77 | <0.001 | |
| Post | 21.9±2.8 | 26.1±2.2 | ||||||
| SAS | Pre | 48.6±6.6 | 13.42 | 0.001 | 48.1±5.7 | 80.58 | <0.001 | |
| Post | 45.2±5.3 | 40.0±5.1 | ||||||
| SDS | Pre | 53.2±7.6 | 11.67 | 0.001 | 52.4±7.8 | 87.45 | <0.001 | |
| Post | 50.0±6.4 | 43.8 ± 5.8 | ||||||
Table 3 Scale scores comparing pre- and post-treatment within EA and SA groups
| Scales | Time | SA group (n = 33) | EA group (n = 34) | |||||
|---|---|---|---|---|---|---|---|---|
| F value | P value | F value | P value | |||||
| PSQI | Pre | 13.7±2.0 | 10.66 | 0.002 | 14.6±2.7 | 311.67 | <0.001 | |
| Post | 12.2±1.5 | 7.1±2.4 | ||||||
| MoCA_B | Pre | 19.5±4.3 | 26.88 | <0.001 | 19.6±4.0 | 203.77 | <0.001 | |
| Post | 21.9±2.8 | 26.1±2.2 | ||||||
| SAS | Pre | 48.6±6.6 | 13.42 | 0.001 | 48.1±5.7 | 80.58 | <0.001 | |
| Post | 45.2±5.3 | 40.0±5.1 | ||||||
| SDS | Pre | 53.2±7.6 | 11.67 | 0.001 | 52.4±7.8 | 87.45 | <0.001 | |
| Post | 50.0±6.4 | 43.8 ± 5.8 | ||||||
Figure 1 Main FC enhanced areas of DMN in the EA group before treatment FC: functional connectivity; DMN: default mode network; EA: electroacupuncture group.
Figure 1 Main FC enhanced areas of DMN in the EA group before treatment FC: functional connectivity; DMN: default mode network; EA: electroacupuncture group.
Figure 2 Main FC weakened areas of DMN in the EA group after treatment FC: functional connectivity; DMN: default mode network; EA: electroacupuncture group.
Figure 2 Main FC weakened areas of DMN in the EA group after treatment FC: functional connectivity; DMN: default mode network; EA: electroacupuncture group.
Figure 3 Main FC enhanced areas of CCN in the EA group after treatment FC: functional connectivity; CCN: cognitive control network EA: electroacupuncture group.
Figure 3 Main FC enhanced areas of CCN in the EA group after treatment FC: functional connectivity; CCN: cognitive control network EA: electroacupuncture group.
Figure 4 Plane visualization of the significant results of continuous edges analysis in the EA group after treatment EA: electroacupuncture group. The Thalamus.L, Hippocampus.L, and Occipital.mid.L were the key nodes.
Figure 4 Plane visualization of the significant results of continuous edges analysis in the EA group after treatment EA: electroacupuncture group. The Thalamus.L, Hippocampus.L, and Occipital.mid.L were the key nodes.
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