Journal of Traditional Chinese Medicine ›› 2023, Vol. 43 ›› Issue (1): 146-153.DOI: 10.19852/j.cnki.jtcm.2023.01.013
• Original articles • Previous Articles Next Articles
JIN Yutong1, WU Lingtao2, GUO Yanglu1, XIA Chong3, YU Binyan1, XUAN Lihua1()
Received:
2022-06-26
Accepted:
2022-10-18
Online:
2023-02-15
Published:
2023-01-10
Contact:
XUAN Lihua
About author:
Prof. XUAN Lihua, Department of Acupuncture and Moxibustion, the First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, China. xlh1083@163.com. Telephone:+86-13588420630Supported by:
JIN Yutong, WU Lingtao, GUO Yanglu, XIA Chong, YU Binyan, XUAN Lihua. Long-term efficacy of point application therapy on different acupoints and durations in the treatment of asthma: a randomized controlled trial[J]. Journal of Traditional Chinese Medicine, 2023, 43(1): 146-153.
Item | 12 acupoints × 2 h | 12 acupoints × 4 h | 6 acupoints × 2 h | Total | F/χ2 value | P value | ||
---|---|---|---|---|---|---|---|---|
Age (years) | Mean | 43.28 | 43.59 | 43.27 | 43.38 | 0.046 | 0.956 | |
SD | 10.41 | 10.09 | 10.23 | 10.22 | ||||
Median | 43.0 | 43.5 | 43.0 | 43.0 | ||||
Min | 18 | 18 | 22 | 18 | ||||
Max | 65 | 65 | 65 | 65 | ||||
Sex [n (%)] | male | 58 (39.5) | 59 (39.3) | 50 (34.2) | 167 (37.7) | 1.105 | 0.576 | |
female | 89 (60.5) | 91 (60.7) | 96 (65.8) | 276 (62.3) | ||||
Height (m) | Mean | 1.64 | 1.65 | 1.64 | 1.65 | 1.021 | 0.361 | |
SD | 0.07 | 0.07 | 0.08 | 0.08 | ||||
Median | 1.63 | 1.63 | 1.63 | 1.63 | ||||
Min | 1.5 | 1.5 | 1.5 | 1.5 | ||||
Max | 1.9 | 1.9 | 1.9 | 1.9 | ||||
Weight (kg) | Mean | 60.24 | 61.50 | 60.11 | 60.62 | 0.301 | 0.740 | |
SD | 8.95 | 9.44 | 9.33 | 9.25 | ||||
Median | 60.00 | 60.00 | 60.00 | 60.00 | ||||
Min | 40.0 | 40.0 | 40.0 | 40.0 | ||||
Max | 86.0 | 86.0 | 82.0 | 86.0 |
Table 1 Baseline characteristics
Item | 12 acupoints × 2 h | 12 acupoints × 4 h | 6 acupoints × 2 h | Total | F/χ2 value | P value | ||
---|---|---|---|---|---|---|---|---|
Age (years) | Mean | 43.28 | 43.59 | 43.27 | 43.38 | 0.046 | 0.956 | |
SD | 10.41 | 10.09 | 10.23 | 10.22 | ||||
Median | 43.0 | 43.5 | 43.0 | 43.0 | ||||
Min | 18 | 18 | 22 | 18 | ||||
Max | 65 | 65 | 65 | 65 | ||||
Sex [n (%)] | male | 58 (39.5) | 59 (39.3) | 50 (34.2) | 167 (37.7) | 1.105 | 0.576 | |
female | 89 (60.5) | 91 (60.7) | 96 (65.8) | 276 (62.3) | ||||
Height (m) | Mean | 1.64 | 1.65 | 1.64 | 1.65 | 1.021 | 0.361 | |
SD | 0.07 | 0.07 | 0.08 | 0.08 | ||||
Median | 1.63 | 1.63 | 1.63 | 1.63 | ||||
Min | 1.5 | 1.5 | 1.5 | 1.5 | ||||
Max | 1.9 | 1.9 | 1.9 | 1.9 | ||||
Weight (kg) | Mean | 60.24 | 61.50 | 60.11 | 60.62 | 0.301 | 0.740 | |
SD | 8.95 | 9.44 | 9.33 | 9.25 | ||||
Median | 60.00 | 60.00 | 60.00 | 60.00 | ||||
Min | 40.0 | 40.0 | 40.0 | 40.0 | ||||
Max | 86.0 | 86.0 | 82.0 | 86.0 |
Item | 12 acupoints × 2 h | 12 acupoints × 4 h | 6 acupoints × 2 h | Total | Z value | P value | |
---|---|---|---|---|---|---|---|
Mean | 155.81 | 144.93 | 115.60 | 138.88 | 3.659 | 0.161 | |
SD | 137.84 | 125.34 | 92.69 | 121.15 | |||
Median | 108.0 | 120.0 | 96.0 | 108.0 | |||
Min | 12 | 3 | 12 | 3 | |||
Max | 600 | 600 | 492 | 600 |
Table 2 Course of bronchial asthma baseline
Item | 12 acupoints × 2 h | 12 acupoints × 4 h | 6 acupoints × 2 h | Total | Z value | P value | |
---|---|---|---|---|---|---|---|
Mean | 155.81 | 144.93 | 115.60 | 138.88 | 3.659 | 0.161 | |
SD | 137.84 | 125.34 | 92.69 | 121.15 | |||
Median | 108.0 | 120.0 | 96.0 | 108.0 | |||
Min | 12 | 3 | 12 | 3 | |||
Max | 600 | 600 | 492 | 600 |
Item | 12 acupoints × 2 h | 12 acupoints × 4 h | 6 acupoints × 2 h | Total | Z value | P value | |
---|---|---|---|---|---|---|---|
Mean | 4.31 | 4.40 | 4.75 | 4.48 | 0.628 | 0.731 | |
SD | 2.91 | 3.07 | 3.36 | 3.11 | |||
Median | 4.0 | 4.0 | 4.0 | 4.0 | |||
Min | 0 | 0 | 0 | 0 | |||
Max | 12 | 15 | 14 | 15 |
Table 3 Baseline comparison of asthma attacks
Item | 12 acupoints × 2 h | 12 acupoints × 4 h | 6 acupoints × 2 h | Total | Z value | P value | |
---|---|---|---|---|---|---|---|
Mean | 4.31 | 4.40 | 4.75 | 4.48 | 0.628 | 0.731 | |
SD | 2.91 | 3.07 | 3.36 | 3.11 | |||
Median | 4.0 | 4.0 | 4.0 | 4.0 | |||
Min | 0 | 0 | 0 | 0 | |||
Max | 12 | 15 | 14 | 15 |
Figure 1 Herbal acupoint sticking method A: paster; B: treatment group 3 acupoint selection, Feishu (BL13), Xinshu (BL15), and Geshu (BL17); C, D: Treatment group 1 and 2 acupoint selection, Dazhui (GV14), Feishu (BL13), Xinshu (BL15), Geshu (BL17), Pishu (BL20), Shenshu (BL23), and Guanyuan (CV4).
Group | n | Before treatment | 1 year after treatment |
---|---|---|---|
Treatment group 1 | 147 | 4.3±2.9 | 2.1±2.1abc |
Treatment group 2 | 150 | 4.4±3.1 | 2.6±2.3a |
Treatment group 3 | 146 | 4.7±3.4 | 3.4±2.7a |
Table 4 Comparisons of the number of attacks before and after treatment in each group of patients with asthma (n, $\bar{x}\pm s$)
Group | n | Before treatment | 1 year after treatment |
---|---|---|---|
Treatment group 1 | 147 | 4.3±2.9 | 2.1±2.1abc |
Treatment group 2 | 150 | 4.4±3.1 | 2.6±2.3a |
Treatment group 3 | 146 | 4.7±3.4 | 3.4±2.7a |
Group | n | Ineffectiveness | Effectiveness | Significant effectiveness | Clinical remission | Total effective rate (%) |
---|---|---|---|---|---|---|
Treatment group 1 | 147 | 31 | 47 | 49 | 20 | 78.9a |
Treatment group 2 | 150 | 30 | 50 | 56 | 14 | 80.0 |
Treatment group 3 | 146 | 63 | 42 | 39 | 2 | 56.8 |
Table 5 Comparisons of the total clinical efficacy rate after treatment amon g groups of patients with asthma ($\bar{x}\pm s$)
Group | n | Ineffectiveness | Effectiveness | Significant effectiveness | Clinical remission | Total effective rate (%) |
---|---|---|---|---|---|---|
Treatment group 1 | 147 | 31 | 47 | 49 | 20 | 78.9a |
Treatment group 2 | 150 | 30 | 50 | 56 | 14 | 80.0 |
Treatment group 3 | 146 | 63 | 42 | 39 | 2 | 56.8 |
Figure 3 Comparisons of the quality of life scores before and after treatment in each group of patients with asthma After treatment, compared with treatment group 3, aP < 0.05.
Figure 4 Comparisons of serum immunoglobulin E levels before and after treatment in each group of patients with asthma Compared to before treatment within each group, aP < 0.05; after treatment, compared with the treatment group 3, bP < 0.05.
Group | n | Adverse event | Adverse event rate (%) |
---|---|---|---|
Treatment group 1 | 147 | 4 | 2.72 |
Treatment group 2 | 150 | 7 | 4.67 |
Treatment group 3 | 146 | 2 | 1.37 |
Table 6 Adverse event rate ($\bar{x}\pm s$)
Group | n | Adverse event | Adverse event rate (%) |
---|---|---|---|
Treatment group 1 | 147 | 4 | 2.72 |
Treatment group 2 | 150 | 7 | 4.67 |
Treatment group 3 | 146 | 2 | 1.37 |
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