Journal of Traditional Chinese Medicine ›› 2024, Vol. 44 ›› Issue (4): 633-641.DOI: 10.19852/j.cnki.jtcm.20240626.001
• Meta-analysis • Next Articles
CHEN Dandan1, JIN Qianhong2, SHEN Yuanjuan2, WANG Qing3, DAI Zhengxiang4()
Received:
2023-01-22
Accepted:
2023-08-08
Online:
2024-08-15
Published:
2024-06-26
Contact:
DAI Zhengxiang, Hospital Infection Control Office, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210004, China. Supported by:
CHEN Dandan, JIN Qianhong, SHEN Yuanjuan, WANG Qing, DAI Zhengxiang. Scraping therapy for knee osteoarthritis: a systematic review and Meta-analysis[J]. Journal of Traditional Chinese Medicine, 2024, 44(4): 633-641.
Study | Sample size (n) (T/C) | Age (years) | Gender (male/ female) | Duration | TCM syndrome pattern | Intervention measure | Frequency /times or duration of scraping | Outcome | |
---|---|---|---|---|---|---|---|---|---|
T | C | ||||||||
Deng YL et al 2022 | 35/35 | T: 64.7±4.7 C: 64.5±4.8 | T: 15/20 C: 13/22 | T: 3.26±1.02 yr C:3.43±1.05 yr | n.r. | Holographic scraping+ Celecoxib capsules | Celecoxib capsules | 1 d, 14 times | ② ④ |
Zhu WT et al 2022 | 25/25 | T: 58.88±3.47 C: 56.96±3.52 | T: 7/18 C: 8/17 | T: 12.84 ± 1.02 m C: 16.32± 1.02 m | n.r. | Copper scraping+ Haohuo needle | Haohuo needle | 3 to 5 d, 5 times | ④ ⑧ |
Guo YG et al 2021 | 50/50 | T: 48.26±1.95 C: 48.43±2.14 | T: 29/21 C: 28/22 | n.r. | liver and kidney deficiency | Scraping+Routine care | Acupuncture+ routine care | 1 week, 10 times | ② ③ |
Xu FY et al 2021 | 30/30 | T: 52.83±5.06 C: 53.26±4.03 | T: 16/14 C: 18/12 | T: 3.59±1.14 yr C: 3.61±1.17 yr | cold and stasis obstruction collateral | Hufu copper scraping + Symptomatic care | Symptomatic care | 3 to 5 d, 1 month | ① ② ⑤ |
Bao SY et al 2020 | 24/24 | T: 64.97±6.23 C: 65.37±6.15 | T: 12/12 C: 10/14 | T: 2.10±0.38 yr C: 1.99±0.23 yr | n.r. | Hufu copper scraping+ Health care | Routine clinical treatment+health care | 1 week, 12 times | ② |
Zheng JX et al 2019 | 80/80 | T: 51.58±9.53 C: 54.13±10.16 | T: 22/18 C: 22/18 | T: 3.68±2.13 yr C: 3.48±2.45 yr | n.r. | Hufu copper scraping+ Scraping + routine drug therapy and care | Routine drug therapy and care | 5-7 d, 12 times | ② ③ |
Wei JR et al 2018 | 40/40 | T: 67.00±10.54 C: 66.30±11.71 | T: 16/24 C: 18/22 | n.r. | n.r. | Self-functional exercise | Moxibustion+self-functional exercise | 3-5 d, 4 times | ② |
Su LF et al 2017 | 27/27 | n.r. | T: 10/11 C: 7/20 | n.r. | n.r. | Scraping+ Moxibustion | Moxibustion | 3 d, 10 times | ① |
Chen YH 2015 | 30/30 | T: 55.5±4.5 C: 54.6±5.1 | T: 9/21 C: 10/20 | n.r. | liver and kidney deficiency | Scraping | Acupuncture | 3 d, 10 times | ② ② |
Qiu JM et al 2013 | 30/30 | T: 55-62 C: 56-64 | T: 7/23 C: 8/22 | T: 2-5 yr C: 2-5 yr | n.r. | Scraping+ Shenmai needle | Shenmai needle | 3 d, 15 times | ⑤ |
Bian XF 2012 | 98/102 | T: 48-82 C: n.r. | T: 30/68 C: n.r. | T: 3 m-35 yr C: n.r. | n.r. | Scraping+ Dahuoluo Pill | Acupuncture+Dahuoluo Pill | 3 d, 5 times | ① |
Liu ZD et al 2011 | 30/30 | T: 60.57±1.79 C: 61.10±1.98 | T: 12/18 C: 13/17 | T: 6.39±1.44 yr C: 6.59±0.95 yr | n.r. | Scraping+ Glucosamine sulfate capsules | Glucosamine sulfate capsules | 1 week, twice | ③ |
Table 1 Main characteristics of included studies
Study | Sample size (n) (T/C) | Age (years) | Gender (male/ female) | Duration | TCM syndrome pattern | Intervention measure | Frequency /times or duration of scraping | Outcome | |
---|---|---|---|---|---|---|---|---|---|
T | C | ||||||||
Deng YL et al 2022 | 35/35 | T: 64.7±4.7 C: 64.5±4.8 | T: 15/20 C: 13/22 | T: 3.26±1.02 yr C:3.43±1.05 yr | n.r. | Holographic scraping+ Celecoxib capsules | Celecoxib capsules | 1 d, 14 times | ② ④ |
Zhu WT et al 2022 | 25/25 | T: 58.88±3.47 C: 56.96±3.52 | T: 7/18 C: 8/17 | T: 12.84 ± 1.02 m C: 16.32± 1.02 m | n.r. | Copper scraping+ Haohuo needle | Haohuo needle | 3 to 5 d, 5 times | ④ ⑧ |
Guo YG et al 2021 | 50/50 | T: 48.26±1.95 C: 48.43±2.14 | T: 29/21 C: 28/22 | n.r. | liver and kidney deficiency | Scraping+Routine care | Acupuncture+ routine care | 1 week, 10 times | ② ③ |
Xu FY et al 2021 | 30/30 | T: 52.83±5.06 C: 53.26±4.03 | T: 16/14 C: 18/12 | T: 3.59±1.14 yr C: 3.61±1.17 yr | cold and stasis obstruction collateral | Hufu copper scraping + Symptomatic care | Symptomatic care | 3 to 5 d, 1 month | ① ② ⑤ |
Bao SY et al 2020 | 24/24 | T: 64.97±6.23 C: 65.37±6.15 | T: 12/12 C: 10/14 | T: 2.10±0.38 yr C: 1.99±0.23 yr | n.r. | Hufu copper scraping+ Health care | Routine clinical treatment+health care | 1 week, 12 times | ② |
Zheng JX et al 2019 | 80/80 | T: 51.58±9.53 C: 54.13±10.16 | T: 22/18 C: 22/18 | T: 3.68±2.13 yr C: 3.48±2.45 yr | n.r. | Hufu copper scraping+ Scraping + routine drug therapy and care | Routine drug therapy and care | 5-7 d, 12 times | ② ③ |
Wei JR et al 2018 | 40/40 | T: 67.00±10.54 C: 66.30±11.71 | T: 16/24 C: 18/22 | n.r. | n.r. | Self-functional exercise | Moxibustion+self-functional exercise | 3-5 d, 4 times | ② |
Su LF et al 2017 | 27/27 | n.r. | T: 10/11 C: 7/20 | n.r. | n.r. | Scraping+ Moxibustion | Moxibustion | 3 d, 10 times | ① |
Chen YH 2015 | 30/30 | T: 55.5±4.5 C: 54.6±5.1 | T: 9/21 C: 10/20 | n.r. | liver and kidney deficiency | Scraping | Acupuncture | 3 d, 10 times | ② ② |
Qiu JM et al 2013 | 30/30 | T: 55-62 C: 56-64 | T: 7/23 C: 8/22 | T: 2-5 yr C: 2-5 yr | n.r. | Scraping+ Shenmai needle | Shenmai needle | 3 d, 15 times | ⑤ |
Bian XF 2012 | 98/102 | T: 48-82 C: n.r. | T: 30/68 C: n.r. | T: 3 m-35 yr C: n.r. | n.r. | Scraping+ Dahuoluo Pill | Acupuncture+Dahuoluo Pill | 3 d, 5 times | ① |
Liu ZD et al 2011 | 30/30 | T: 60.57±1.79 C: 61.10±1.98 | T: 12/18 C: 13/17 | T: 6.39±1.44 yr C: 6.59±0.95 yr | n.r. | Scraping+ Glucosamine sulfate capsules | Glucosamine sulfate capsules | 1 week, twice | ③ |
Figure 3 Results of the Meta-analysis A: forest plot of the overall effective rate; B: forest plot of the overall effective rate (sensitivity analysis); C: forest plot of the VAS score; D: forest plot of the VAS score (sensitivity analysis); E: forest plot of the Lysholm score; F: forest plot of the WOMAC score; G: forest plot of the HSS score; VAS: visual analog scale; WOMAC: Western Ontario and McMaster University Osteoarthritis Index; HSS: Hospital for Special Surgery; Random: random-effects model; Fixed: fixed-effects model; SD: standard deviation; CI: confidence interval.
Figure 4 GRADE evidence profile GRADE: Grades of Recommendations Assessment, Development and Evaluation; VAS: visual analog scale; WOMAC: Western Ontario and McMaster University Osteoarthritis Index; HSS: Hospital for Special Surgery; RR: risk ratio; CI: confidence interval; MD: mean difference.
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