Journal of Traditional Chinese Medicine ›› 2023, Vol. 43 ›› Issue (1): 198-204.DOI: 10.19852/j.cnki.jtcm.20221108.003
• Review • Previous Articles
XUE Nannan1, JIA Liyang2, LI Qiyan2()
Received:
2021-11-11
Accepted:
2022-02-08
Online:
2023-02-15
Published:
2023-01-10
Contact:
LI Qiyan
About author:
Prof. LI Qiyan, Department of Stomatology, the First People’s Hospital of Yunnan Province. The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, China. ynliqiyan@aliyun.com. Telephone:+86-871-15368088803Supported by:
XUE Nannan, JIA Liyang, LI Qiyan. Potential of natural medicines for treatment of osteoporosis: a narrative review[J]. Journal of Traditional Chinese Medicine, 2023, 43(1): 198-204.
1 |
Cohen AJ, Roe FJ. Review of risk factors for osteoporosis with particular reference to a possible aetiological role of dietary salt. Food Chem Toxicol 2000; 38: 237-53.
PMID |
2 | Chowdhury B, Seetharam A, Wang Z, et al. A Study of alterations in DNA epigenetic modifications (5mC and 5hmC) and gene expression influenced by simulated microgravity in human lymphoblastoid cells. PLoS One 2016; 11 :1-29. |
3 |
Chowdhury P, Soulsby M. Lipid peroxidation in rat brain is increased by simulated weightlessness and decreased by a soy-protein diet. Ann Clin Lab Sci 2002; 32: 188-92.
PMID |
4 | Song SH, Gao ZY, Lei XJ, et al. Total flavonoids of Drynariae Rhizoma prevent bone loss induced by hindlimb unloading in rats. Molecules 2017; 22: 1033-49. |
5 |
Shujian C, Chen W, Yang J. Another formula for calculating the gene change rate in real-time RT-PCR. Mol Biol Rep 2009; 36: 2165-8.
DOI PMID |
6 | Li L, Seeram NP. Further investigation into maple syrup yields 3 new lignans, a new phenylpropanoid, and 26 other phytochemicals. J Agric Food Chem 2011; 59: 7708-16. |
7 |
Valverde P. Pharmacotherapies to manage bone loss-associated diseases: a quest for the perfect benefit-to-risk ratio. Curr Med Chem 2008; 15: 284-304.
DOI PMID |
8 |
MacDonald BT, Tamai K, He X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 2009; 17: 9-26.
DOI PMID |
9 | Bin Q, Shenghua L, Mingwang Z, Pingfu J. Research progress of the correlation between Wnt/ -catenin signaling pathway and cartilage metabolism. Chin J Tradit Med Traumatol Orthop 2016; 10: 75-7. |
10 | Amjadi-Moheb F, Akhavan-Niaki H. Wnt signaling pathway in osteoporosis: epigenetic regulation, interaction with other signaling pathways, and therapeutic promises. J Cell Phys 2019; 9: 14641-50. |
11 |
Baksh D, Boland GM, Tuan RS. Cross-talk between Wnt signaling pathways in human mesenchymal stem cells leads to functional antagonism during osteogenic differentiation. J Cell Biochem 2007; 101: 1109-24.
PMID |
12 | Molagoda IMN, Karunarathne WAHM, Choi YH, et al. Fermented Oyster extract promotes osteoblast differentiation by activating the Wnt/beta-catenin signaling pathway, leading to bone formation. Biomolecules 2019; 9: 711-29. |
13 | Ricardo C, de Sousa EM, Botelho JN, et al. Bone substitute made from a Brazilian oyster shell functions as a fast stimulator for bone-forming cells in an animal model. PLoS One 2018; 13: e0198697. |
14 | Lee YK, Jung SK, Chang YH, Kwak HS. Highly bioavailable nanocalcium from oyster shell for preventing osteoporosis in rats. Int J Food Sci Nutr 2017; 68: 931-40. |
15 | Brogi S, Maramai S, Brindisi M, et al. Activation of the Wnt pathway by small peptides: rational design, synthesis and biological evaluation. Chem Med Chem 2017; 12: 2074-85. |
16 | Chen Y, Li YQ, Fang JY, Li P, Li F. Establishment of the con-current experimental model of osteoporosis combined with Alzheimer's disease in rat and the dual-effects of echinacoside and acteoside from Cistanche tubulosa. J Ethnopharmacol 2020; 15: 257. |
17 |
Jiang Y, Tu PF. Analysis of chemical constituents in Cistanche species. J Chromatogr A 2009; 1216: 1970-9.
DOI PMID |
18 | Li Z, Lin H, Gu L, Gao J, Tzeng CM. Herba Cistanche (Rou Cong-Rong): one of the best pharmaceutical gifts of Traditional Chinese Medicine. Front Pharmacol 2016; 7: 41. |
19 | Wang T, Zhang X, Xie W. Cistanche deserticola Y. C. Ma, "Desert ginseng": a review. Am J Chin Med 2012; 40: 1123-41. |
20 | Gang Z, HaiBin S, Gang X. Therapeutic effect of cistanche deserticola ethanol extraction in rats with osteoporsis induced by ovariectomy and its mechanism. Jilin Da Xue Xue Bao 2018; 44: 68-72. |
21 | Xing XY, Liu ZJ, Han B. Effects of water extract of Cistanche deserticola on expression of bone morphogenetic protein 2 gene in rat osteoblasts. CHI Ani Hus Vet Med 2013; 40: 17-21. |
22 | Wang F, Tu P, Zeng K, Jiang Y. Total glycosides and polysaccharides of Cistanche deserticola prevent osteoporosis by activating Wnt/β-catenin signaling pathway in SAMP6 mice. J Ethnopharmacol 2021; 10: 271. |
23 |
Amin N, Boccardi V, Taghizadeh M, Jafarnejad S. Probiotics and bone disorders: the role of RANKL/RANK/OPG pathway. Aging Clin Exp Res 2020; 32: 363-71.
DOI PMID |
24 | Xue JB, Zhan XL, Wang WJ, Yan YG, Liu C. OPG rs2073617 polymorphism is associated with upregulated OPG protein expression and an increased risk of intervertebral disc degeneration. Exp Ther Med 2016; 12: 702-10. |
25 | Xu S, Zhang Y, Liu B, et al. Activation of mTORC1 in B lymphocytes promotes osteoclast formation via regulation of β-catenin and RANKL/OPG. J Bone Miner Res 2016; 31: 1320-33. |
26 | Siar CH, Tsujigiwa H, Ishak I, Hussin NM, Nagatsuka H, Ng KH. RANK, RANKL, and OPG in recurrent solid/multicystic ameloblastoma: their distribution patterns and biologic significance. Oral Surg Oral Med Oral Pathol Oral Radiol 2015; 119: 83-91. |
27 | Lu JC, Liu F, Liu D, et al. Amlodipine and atorvastatin improved hypertensive cardiac hypertrophy through regulation of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin system in spontaneous hypertension rats. Exp Biol Med 2016; 241: 1237-49. |
28 |
Sun J, Sun B, Wang W, et al. Histochemical examination of the effects of high-dose 1,25(OH)2D3 on bone remodeling in young growing rats. J Mol Histol 2016; 47: 389-99.
DOI PMID |
29 | Xiong MY, Liu LQ, Liu SQ, Liu ZH, Gao HF. Effects of osteoprotegerin, RANK and RANKL on bone destruction and collapse in avascular necrosis femoral head. Am J Transl Res 2016; 8: 3133-40. |
30 |
Gonda R, Tomoda M, ShimizuN, Kanari M. Characterization of an acidic polysaccharide from the seeds of Malva verticillata stimulating the phagocytic activity of cells of the RES. Planta Med 1990; 56: 73-6.
PMID |
31 |
Tomoda M, Shimizu N, Gonda R, et al. Anti-complementary and hypoglycemic activities of the Glycans from the seeds of Malva verticillata. Planta Med 1990; 56: 168-70.
PMID |
32 |
Miyamoto T. Regulators of osteoclast differentiation and cell-cell fusion. Keio J Med 2011; 60: 101-5.
PMID |
33 | Kim T, Kim K, Lee SH, et al. Identification of LRRc17 as a negative regulator of receptor activator of NF-κB ligand (RANKL)-induced osteoclast differentiation. J Biol Chem 2009;284: 15308-16. |
34 | Crockett JC, Das S. Osteoporosis – a current view of pharmacological prevention and treatment. Drug Des Dev Ther 2013; 7: 435-48. |
35 | Uddin MK, Juraimi AS, Hossain MS, Nahar MA, Ali ME, Rahman MM. Purslane weed (Portulaca oleracea): a prospective plant source of nutrition, omega-3 fatty acid, and antioxidant attributes. Sci World J 2014; 2014:1-6. |
36 |
Miao L, Tao H, Peng Y, et al. The anti-inflammatory potential of Portulaca oleracea L. (purslane) extract by partial suppression on NF-κB and MAPK activation. Food Chem 2019; 290: 239-45.
DOI PMID |
37 | Chan K, Islam MW, Kamil M, et al. The analgesic and anti-inflammatory effects of Portulaca oleracea L. subsp. sativa (Haw.) Celak. J Ethnopharmacol 2000; 73: 445-51. |
38 |
Rúben S, Carvalho IS. In vitro antioxidant activity, phenolic compounds and protective effect against DNA damage provided by leaves, stems and flowers of Portulaca oleracea (Purslane). Nat Prod Commun 2014; 9: 45-50.
PMID |
39 | Kim JY, Oh HM, Kwak SC, et al. Purslane suppresses osteoclast differentiation and bone resorbing activity via inhibition of Akt/GSK3β-c-Fos-NFATc1 signaling in vitro and prevents lipopolysaccharide-induced bone loss in vivo. Biol Pharm Bull 2015; 38: 66-74. |
40 | Moon JB, Kim JH, Kim K, et al. Akt induces osteoclast differentiation through regulating the GSK3beta/NFATc1 signaling cascade. J Immunol 2012; 188: 163-9. |
41 |
Kim JM, Yun-Choi HS. Anti-platelet effects of flavonoids and flavonoid-glycosides from Sophora japonica. Arch Pharm Res 2008; 31: 886-90.
DOI PMID |
42 |
Park KW, Lee JE, Park KM. Diets containing Sophora japonica L. prevent weight gain in high-fat diet-induced obese mice. Nutr Res 2009; 29: 819-24.
DOI PMID |
43 |
Kim BH, Chung EY, Min BK, et al. Anti-inflammatory action of Legume Isoflavonoid Sophoricoside through inhibition on cyclooxygenase-2 activity. Planta Med 2003; 69: 474-6.
PMID |
44 |
Takayanagi H, Kim S, Koga T, et al. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev Cell 2002; 3: 889-901.
DOI PMID |
45 |
Asagiri M, Sato K, Usami T, et al. Autoamplification of NFATc1 expression determines its essential role in bone homeostasis. J Exp Med 2005; 202: 1261-9.
DOI PMID |
46 | Kim K, Lee SH, Ha Kim J, et al. NFATc1 induces osteoclast fusion via up-regulation of Atp6v0d2 and the dendritic cell-specific transmembrane protein (DC-STAMP). Mol Endocrinol 2008; 22: 176-85. |
47 | Koga T, Inui M, Inoue K, et al. Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis. Nature 2008; 428: 758-63. |
48 | Kim JM, Lee JH, Lee GS, et al. Sophorae Flos extract inhibits RANKL-induced osteoclast differentiation by suppressing the NF-κB/NFATc1 pathway in mouse bone marrow cells. BMC Complement Altern Med 2017; 17: 164-71. |
49 | Hirata T, Ikeda T, Fujikawa T, Nishibe S. The chemistry and bioactivity of Eucommia ulmoides Oliver leaves. Stud Nat Prod Chem 2014; 41: 225-60. |
50 | Dai XP, Huang Q, Zhou BT, Gong Z, Liu Z, Shi S. Preparative isolation and purification of seven main antioxidants from Euco-mmia ulmoides Oliv. (Du-zhong) leaves using HSCCC guided by DPPH-HPLC experiment. Food chem 2013; 139: 563-70. |
51 | Lee DM, Weinblatt ME. Rheumatoid arthritis. Lancet (London, England) 2001; 358: 903-11. |
52 | Huang L, Lyu Q, Zheng W, et al. Traditional application and modern pharmacological research of Eucommia ulmoides Oliv. Chin Med 2021; 16: 73. |
53 |
Deyama T, Nishibe S, Nakazawa Y. Constituents and pharmacological effects of Eucommia and Siberian ginseng. Acta Pharmacol Sin 2001; 22: 1057-70.
PMID |
54 |
Zhang R, Liu ZG, Li C, et al. Du-Zhong (Eucommia ulmoides Oliv.) cortex extract prevent OVX-induced osteoporosis in rats. Bone 2009; 45: 553-9.
DOI PMID |
55 | Kim B, Lim DW, Song J, Kim H. Anti-osteoporotic effect of Eucommia ulmoides cortex in ovariectomized rats. Planta Med 2012; 78: 76. |
56 |
Zhang R, Pan YL, Hu SJ, Kong XH, Juan W, Mei QB. Effects of total lignans from Eucommia ulmoides barks prevent bone loss in vivo and in vitro. J Ethnopharmacol 2014; 155: 104-12.
DOI PMID |
57 | Kim JA, Karadeniz F, Ahn BN, et al. Bioactive quinone derivatives from the marine brown alga Sargassum thunbergii induce anti-adipogenic and pro-osteoblastogenic activities. J Sci Food Agric 2016 96: 783-804. |
58 |
Liu L, Heinrich M, Myers S, Dworjanyn SA. Towards a better understanding of medicinal uses of the brown seaweed Sargassum in Traditional Chinese Medicine: a phytochemical and pharmacological review. J Ethnopharmacol 2012; 142: 591-619.
DOI PMID |
59 |
Hwang CS, Loftus TM, Mandrup S, Lane MD. Adipocyte differentiation and leptin expression. Annu Rev Cell Dev Biol 1997; 13: 231-59.
PMID |
60 | Chen X, Zhi X, Yin Z, et al. 18beta-glycyrrhetinic acid inhibits osteoclastogenesis in vivo and in vitro by blocking RANKL-mediated RANK-TRAF 6 interactions and NF-kappa B and MAPK signaling pathways. Front Pharmacol 2018; 9: 647. |
61 | Kim HJ, Park C, Kim GY, et al. Sargassum serratifolium attenuates RANKL-induced osteoclast differentiation and oxidative stress through inhibition of NF-κB and activation of the Nrf2/HO-1 signaling pathway. Biosci Trends 2018; 12: 257-65. |
62 | Idris OA, Wintola OA, Afolayan AJ. Evaluation of the bioactivities of Rumex crispus L. leaves and root extracts using toxicity, antimicrobial, and antiparasitic assays. Evid Based Complement Alternat Med 2019; 1-13. |
63 | Lee S, Kim D, Yim D. Anti-inflammatory, analgesic and hepatoprotective effect of semen of Rumex crispus. Korean J Pharm 2007; 38: 334-8. |
64 | Shim KS, Lee B, Ma JY. Water extract of Rumex crispus prevents bone loss by inhibiting osteoclastogenesis and inducing osteoblast mineralization. BMC Complement Altern Med 2017; 17: 483-91. |
65 |
Shiwani S, Singh NK, Wang MH. Carbohydrase inhibition and anti-cancerous and free radical scavenging properties along with DNA and protein protection ability of methanolic root extracts of Rumex crispus. Nutr Res Pract 2012; 6: 389-95.
DOI PMID |
66 | Kim JC, Choi GJ, Lee SW, et al. Screening extracts of Achyranthes japonica and Rumex crispus for activity against various plant pathogenic fungi and control of powdery mildew. Pest Manag Sci 2004; 60: 803-8. |
67 | Maksimović Z, Kovacević N, Lakusić B, Cebović T. Antioxidant activity of yellow dock (Rumex crispus L., Polygonaceae) fruit extract. Phytother Res 2011; 25: 101-5. |
68 |
Kanno S, Hirano S, Kayama F. Effects of phytoestrogens and environmental estrogens on osteoblastic differentiation in MC3T3-E1 cells. Toxicology 2004; 196: 137-45.
DOI PMID |
69 |
Tomimori Y, Mori K, Koide M, et al. Evaluation of pharmaceuticals with a novel 50-hour animal model of bone loss. J Bone Miner Res 2009; 24: 1194-205.
DOI PMID |
70 | Li YH, Tan YF, Cai HD, Zhang JQ. Metabonomic study of the fruits of Alpinia oxyphylla as an effective treatment for chronic renal injury in rats. J Pharm Biomed Anal 2016; 124: 236-45. |
71 | Wang CA, Yuan HH, Bao XL, Lan MB. In vitro antioxidant and cytotoxic properties of ethanol extract of Alpinia oxyphylla fruits. PharmBiol 2013; 51: 1419-25. |
72 | Shin TY, Won JH, Kim HM, Kim SH. Effect of Alpinia oxyphylla fruit extract on compound 48/80-induced anaphylactic reactions. Am J Chin Med 2001; 29: 293-302. |
73 | Yamahara J, Li YH, Tamai Y. Anti-ulcer effect in rats of bitter cardamon constituents. Chem Pharm Bull (Tokyo) 1990; 38: 3053-4. |
74 | Zhang ZJ, Cheang LC, Wang MW, et al. Ethanolic extract of fructus Alpinia oxyphylla protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish. Cell Mol Neurobiol 2012; 32: 27-40. |
75 |
Yu X, An L, Wang L, Zhao H, Gao C. Neuroprotective effect of Alpinia oxyphylla Miq. fruits against glutamate-induced apoptosis in cortical neurons. Toxicol Lett 2003; 144: 205-12.
PMID |
76 |
Matsuo K, Galson DL, Zhao C, et al. Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos. J Biol Chem 2004; 279: 26475-80.
DOI PMID |
77 |
Kim K, Kim JH, Lee J, et al. MafB negatively regulates RANKL-mediated osteoclast differentiation. Blood 2007; 109: 3253-9.
DOI PMID |
78 | Ha H, Shim KS, Kim HT, et al. Water extract of the fruits of Alpinia oxyphylla inhibits osteoclast differentiation and bone loss. BMC Complement Altern Med 2014; 14: 352-61. |
79 |
Santibanez JF, Kocic J. Transforming growth factor-β superfamily, implications in development and differentiation of stem cells. Biomol Concepts 2012; 3: 429-45.
DOI PMID |
80 | Wang MK, Sun HQ, Xiang YC, et al. Different roles of TGF-β in the multi-lineage differentiation of stem cells. World J Stem Cells 2012; 4: 28-34. |
81 | Chen M, Lv Z, Jiang S. The effects of triptolide on airway remo-delling and transforming growth factor-β₁/Smad signalling path-way in ovalbumin-sensitized mice. Immunology 2011; 132: 376-84. |
82 |
Langdahl BL, Carstens M, Stenkjaer L, Eriksen EF. Polymorphisms in the transforming growth factor beta 1 gene and osteoporosis. Bone 2003; 32: 297-310.
DOI PMID |
83 | Huang W, Yang S, Shao J, Li YP. Signaling and transcriptional regulation in osteoblast commitment and differentiation. Front Biosci 2007; 12: 3068-92. |
84 | Song B, Estrada KD, Lyons KM. Smad signaling in skeletal development and regeneration. Cytokine Growth Factor Rev 2009; 20: 379-88. |
85 |
Mu Y, Gudey SK, Landström M. Non-Smad signaling pathways. Cell Tissue Res 2012; 347: 11-20.
DOI PMID |
86 | Iegaki N, Narita Y, Hattori N, Hirata Y, Ichihara K. Royal jelly reduces depression-like behavior through possible effects on adrenal steroidogenesis in a murine model of unpredictable chronic mild stress. Biosci Biotechnol Biochem 2020; 84: 606-12. |
87 | Sova O, Grega B, Surzin J. Study on the chemical composition of royal jelly. Cesk Farm 1973; 22: 61-5. |
88 |
Okamoto I, Taniguchi Y, Kunikata T, et al. Major royal jelly protein 3 modulates immune responses in vitro and in vivo. Life Sci 2003; 73: 2029-45.
DOI PMID |
89 |
Bincoletto C, Eberlin S, Figueiredo CA, Luengo MB, Queiroz ML. Effects produced by Royal Jelly on haematopoiesis: relation with host resistance against Ehrlich ascites tumour challenge. Int Immunopharmacol 2005; 5: 679-88.
DOI PMID |
90 | Kamakura M, Mitani N, Fukuda T, Fukushima M. Antifatigue effect of fresh royal jelly in mice. J Nutr Sci Vitaminol (Tokyo) 2001; 47: 394-401. |
91 |
Vittek J. Effect of royal jelly on serum lipids in experimental animals and humans with atherosclerosis. Experientia 1995; 51: 927-35.
PMID |
92 | Matsui T, Yukiyoshi A, Doi S, Sugimoto H, Yamada T, Matsumoto K. Gastrointestinal enzyme production of bioactive peptides from royal jelly protein and their antihypertensive ability in SHR. J Nutr Biochem 2002; 13: 80-6. |
93 | Narita Y, Nomura J, Ohta S, et al. Royal jelly stimulates bone formation: physiologic and nutrigenomic studies with mice and cell lines. Biosci Biotechnol Biochem 2006; 70: 2508-14. |
94 |
Stepan JJ, Alenfeld F, Boivin G, Feyen JH, Lakatos P. Mechanisms of action of antiresorptive therapies of postmenopausal osteoporosis. Endocr Regul 2003; 37: 225-38.
PMID |
95 | Kafadar IH, Güney A, Türk CY, Oner M, Silici S. Royal jelly and bee pollen decrease bone loss due to osteoporosis in an oophorectomized rat model. Eklem Hastalik Cerrahisi 2012; 23: 100-5. |
96 | Kim GH, Baek HK, Lee JS, Kim SJ, Yi SS. Chronic oral administration of Tenebrio molitor extract exhibits inhibitory effect on glucocorticoid receptor overexpression in the hippocampus of ovariectomy-induced estrogen deficient mice. J Food Sci 2019; 84: 687-94. |
97 | Klasing KC, Thacker P, Lopez MA, Calvert CC. Increasing the calcium content of mealworms (Tenebrio molitor) to improve their nutritional value for bone mineralization of growing chicks. J Zoo Wildl Med 2000; 31: 512-7. |
98 | Youn KM, Yu EY, Lee J, et al. Oleic acid and linoleic acid from Tenebrio molitor larvae inhibit BACE1 activity in vitro: molecular docking studies. J Med Food 2014; 17: 284-9. |
99 |
Fabel K, Fabel K, Tam B, et al. VEGF is necessary for exercise-induced adult hippocampal neurogenesis. Eur J Neurosci 2003; 18: 2803-12.
DOI PMID |
[1] | LIU Tingting, LIU Tongou, LIU Mingfu. Effectiveness and safety of acupuncture in treatment of pregnancy-related symptoms: a systematic review and Meta-analysis [J]. Journal of Traditional Chinese Medicine, 2024, 44(1): 16-26. |
[2] | REN Ping, WANG Quanwu, BAI Wei, SUN Miao, LIU Zheling, GAO Ming, WANG Liang, PENG Bo, XU Liguang. Identifying the effective combination of acupuncture and traditional Chinese medicinal herbs for postmenopausal osteoporosis therapy through studies of their molecular regulation of bone homeostasis [J]. Journal of Traditional Chinese Medicine, 2024, 44(1): 212-219. |
[3] | WANG Jiabao, ZHANG Lishuang, NIU Baihan, YU Yajun, YANG Fengwen, MIAO Lin, CHAI Lijuan, DING Xinya, SUN Yingjie, WANG Yujing, WANG Lin, ZHANG Han, WANG Yi, LI Lin. Efficacy and safety of Weichang’ an pill (胃肠安丸) combined with Western Medicine on gastrointestinal diseases: a systematic review and Meta-analysis [J]. Journal of Traditional Chinese Medicine, 2023, 43(6): 1057-1067. |
[4] | FAN Rong, HE Haoyu, TANG Tao, CUI Hanjin. Long-term effects of Qingfei Paidu decoction (清肺排毒汤) in patients with coronavirus disease 2019 acute pneumonia after treatment: a protocol for systematic review and Meta-analysis [J]. Journal of Traditional Chinese Medicine, 2023, 43(6): 1068-1071. |
[5] | WANG Lili, FENG Ju, ZHAN Daqian, WANG Junshuai, ZHOU Daixing. Protective effects of tanshinone ⅡA on sepsis-induced multiple organ dysfunction: a literature review [J]. Journal of Traditional Chinese Medicine, 2023, 43(5): 1040-1046. |
[6] | MEI Pingping, FENG Wenzhe, SHI Peng, ZHANG Wenxiu, ZHUANG Yu. Clinical research progress in Traditional Chinese Medicine in treating wound healing after anal fistula surgery [J]. Journal of Traditional Chinese Medicine, 2023, 43(5): 1047-1054. |
[7] | ZHAO HuiYan, JUN Purumea, LEE Chaewon, HAN Chang-Hyun. Acupoint catgut embedding for simple obesity in animal studies: a systematic review and Meta-analysis [J]. Journal of Traditional Chinese Medicine, 2023, 43(5): 860-867. |
[8] | SUN Wu, ZHAO Yuwei, LIAO Liang, ZHAO Zhonghui, CHEN Shiqi, YAN Xiaoling, WANG Xueyao, CHAO Guojun, ZHOU Jian. Effectiveness and safety of Xuebijing injection for patients with coronavirus disease 2019: a systematic review and Meta-analysis [J]. Journal of Traditional Chinese Medicine, 2023, 43(4): 631-639. |
[9] | MENG Xiangran, CAO Xue, SUN Minglin, AI Yanke, HE Liyun, LIU Jia. Effectiveness and safety of Angong Niuhuang pill (安宫牛黄丸) in treatment of acute stroke: a systematic review and Meta-analysis [J]. Journal of Traditional Chinese Medicine, 2023, 43(4): 650-660. |
[10] | LUO Xin, XIE Jing, HUANG Li, GAN Wenfan, CHEN Ming. Efficacy and safety of activating blood circulation and removing blood stasis of Traditional Chinese Medicine for managing renal fibrosis in patients with chronic kidney disease: a systematic review and Meta-analysis [J]. Journal of Traditional Chinese Medicine, 2023, 43(3): 429-440. |
[11] | MA Fangfang, ZHANG Hewei, LI Bingxue, CHENG Peiyu, YU Mingwei, WANG Xiaomin. Acupuncture and moxibustion for malignant tumor patients with psychological symptoms of insomnia, anxiety and depression: a systematic review and Meta-analysis [J]. Journal of Traditional Chinese Medicine, 2023, 43(3): 441-456. |
[12] | LIU Xueling, MA Kun, TAO Wenhua, XU Zhongkun, LIU Gang, HU Chunyan, MAO Weiwei, GU Chang, GUO Qi. Natural products for treatment of premature ovarian failure: a narrative review [J]. Journal of Traditional Chinese Medicine, 2023, 43(3): 606-617. |
[13] | PENG Wan, NI Hengfan, GUO Dale, DENG Yun, DAI Manyun. Farnesoid X receptor regulators from natural products and their biological function [J]. Journal of Traditional Chinese Medicine, 2023, 43(3): 618-626. |
[14] | GUO Wen, LI Xuanlin, ZHAO Hulei, LEI Siyuan, XIE Yang, LI Jiansheng. Effectiveness of Chinese herbal medicine combined with conventional medicine on acute exacerbation of chronic obstructive pulmonary disease: a systematic review and Meta-analysis [J]. Journal of Traditional Chinese Medicine, 2023, 43(2): 212-220. |
[15] | ZHANG Junli, HE Ying, ZHANG Xia, FU Hongfang, HU Xiaoyu. Fuzheng Huayu preparation (扶正化瘀胶囊/片) combined with tenofovir disoproxil fumarate on hepatitis B: a systematic review and Meta-analysis [J]. Journal of Traditional Chinese Medicine, 2023, 43(2): 221-230. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||
Sponsored by China Association of Chinese Medicine
& China Academy of Chinese Medical Sciences
16 Nanxiaojie, Dongzhimen Nei, Beijing, China. 100700 Email: jtcmen@126.com
Copyright 2020 Journal of Traditional Chinese Medicine. All rights reserved.