Journal of Traditional Chinese Medicine ›› 2023, Vol. 43 ›› Issue (6): 1252-1258.DOI: 10.19852/j.cnki.jtcm.20230919.001
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Traditional Chinese Medicine constitution among patients with allergic rhinitis and its correlation with anxiety and depression
WANG Yaqi1, ZHAO Weibo2, WANG Yixing3, ZHAO Haihong2, ZHOU Yaoyao2, YAN Yun2, WU Taotao2, LUO Bin4(
), WANG Ji5()
- 1 College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China
2 National Institute of Traditional Chinese Medicine Constitution and Preventive Treatment of Diseases, Beijing University of Chinese Medicine, Beijing 100029, China
3 Traditional Chinese Medicine Department, Dongfang Hospital Affiliated to Tongji University, Shanghai 200120, China
4 Journal Center, Beijing University of Chinese Medicine, Beijing 100029, China
5 National Institute of Traditional Chinese Medicine Constitution and Preventive Treatment of Diseases, Beijing University of Chinese Medicine, Beijing 100029, China
-
Received:2022-07-11Accepted:2022-10-20Online:2023-10-25Published:2023-09-19 -
Contact:LUO Bin, Journal Center, Beijing University of Chinese Medicine, Beijing 100029, China. luob@bucm.edu.cn; WANG Ji, National Institute of Traditional Chinese Medicine Constitution and Preventive Treatment of Diseases, Beijing University of Chinese Medicine, Beijing 100029, China. doctorwang2009@ 126.com. Telephone: +86-15538299101 -
Supported by:Research on the Mechanism of Regulating Body Formula Guominkang in Preventing and Treating Allergic Diseases by Regulating the "Bacterial Population PRPs DCs" Axis through Pulmonary Intestinal Co-regulation Based on the "Diagnosing and Treating Different Body Types"(81973715);Study on the Mechanism of Traditional Chinese Medicine Formula "Guo Min Kang" in Preventing Allergic Rhinitis through the "Intestinal Microflora Dendritic Cells" Axis(7202110);Traditional Chinese Medicine Constitution Treatment and Prevention Innovation Team(ZYYCXTD-C-202001)
Cite this article
WANG Yaqi, ZHAO Weibo, WANG Yixing, ZHAO Haihong, ZHOU Yaoyao, YAN Yun, WU Taotao, LUO Bin, WANG Ji. Traditional Chinese Medicine constitution among patients with allergic rhinitis and its correlation with anxiety and depression[J]. Journal of Traditional Chinese Medicine, 2023, 43(6): 1252-1258.
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Table 1 Demographic and health status of subjects [n (%)]
| Characteristic | Total | Anxiety | Depression | |
|---|---|---|---|---|
| Sex | Male | 280 (54.3) | 107 (61.8) | 99 (41.3) |
| Female | 236 (45.7) | 66 (38.2) | 141 (58.8) | |
| Age (years) | ≤17 | 34 (6.6) | 11 (6.4) | 10 (4.2) |
| 18-45 | 351 (50.0) | 134 (77.5) | 188 (78.3) | |
| 46-69 | 124 (19.8) | 28 (16.2) | 41 (17.1) | |
| ≥70 | 7 (1.4) | 0 (0.0) | 1 (0.4) | |
| Region | North | 113 (21.9) | 73 (42.2) | 61 (25.4) |
| Northeast | 223 (43.2) | 18 (10.4) | 101 (42.1) | |
| East | 50 (9.7) | 43 (24.9) | 21 (8.8) | |
| Central | 50 (9.7) | 15 (8.7) | 21 (8.8) | |
| South | 27 (5.2) | 8 (4.6) | 12 (5.0) | |
| Southwest | 25 (4.8) | 6 (3.5) | 13 (5.4) | |
| Northwest | 28 (5.4) | 10 (5.8) | 11 (4.6) | |
| Income | High | 249 (48.3) | 76 (43.9) | 100 (41.7) |
| Medium and below | 267 (51.7) | 97 (56.1) | 140 (58.3) | |
| Body mass index | Non-obese | 342 (66.3) | 97 (56.1) | 136 (56.7) |
| Obesity | 174 (33.7) | 76 (43.9) | 104 (43.3) | |
| Marriage | Single | 246 (47.7) | 89 (51.4) | 114 (47.5) |
| Married | 254 (49.2) | 75 (43.4) | 116 (48.3) | |
| Divorced | 12 (2.3) | 6 (3.5) | 6 (2.5) | |
| Widowed | 4 (0.8) | 3 (1.7) | 4 (1.7) | |
| Smoking or drinking habits | Addicted | 96 (18.6) | 36 (20.8) | 40 (16.7) |
| Not addictive | 420 (81.4) | 137 (79.2) | 200 (83.3) | |
| History of allergic diseases | Yes | 263 (51.0) | 85 (49.1) | 129 (53.8) |
| No | 253 (49.0) | 88 (50.9) | 111 (46.3) | |
| Family history | Yes | 155 (30.0) | 49 (28.3) | 66 (27.5) |
| No | 361 (70.0) | 124 (71.7) | 174 (72.5) | |
| Years of illness | <1 | 88 (17.1) | 29 (16.8) | 40 (16.7) |
| 1-3 | 175 (33.9) | 63 (36.4) | 77 (32.1) | |
| 4-10 | 139 (26.9) | 42 (24.3) | 62 (25.8) | |
| >10 | 114 (22.1) | 39 (22.5) | 61 (25.4) | |
| Allergen | Seasonal | 332 (64.3) | 110 (63.6) | 142 (59.2) |
| Annual | 184 (35.7) | 63 (36.4) | 98 (40.8) | |
| Duration of symptoms | Intermittent | 251 (48.6) | 73 (42.2) | 110 (45.8) |
| Persistent | 265 (51.4) | 100 (57.8) | 130 (54.2) | |
| Severity of illness | Mild | 286 (55.4) | 86 (49.7) | 130 (54.2) |
| Medium-severe | 230 (44.6) | 87 (50.3) | 110 (45.8) | |
| Total | 516 (100.0) | 173 (100.0) | 240 (100.0) |
Table 1 Demographic and health status of subjects [n (%)]
| Characteristic | Total | Anxiety | Depression | |
|---|---|---|---|---|
| Sex | Male | 280 (54.3) | 107 (61.8) | 99 (41.3) |
| Female | 236 (45.7) | 66 (38.2) | 141 (58.8) | |
| Age (years) | ≤17 | 34 (6.6) | 11 (6.4) | 10 (4.2) |
| 18-45 | 351 (50.0) | 134 (77.5) | 188 (78.3) | |
| 46-69 | 124 (19.8) | 28 (16.2) | 41 (17.1) | |
| ≥70 | 7 (1.4) | 0 (0.0) | 1 (0.4) | |
| Region | North | 113 (21.9) | 73 (42.2) | 61 (25.4) |
| Northeast | 223 (43.2) | 18 (10.4) | 101 (42.1) | |
| East | 50 (9.7) | 43 (24.9) | 21 (8.8) | |
| Central | 50 (9.7) | 15 (8.7) | 21 (8.8) | |
| South | 27 (5.2) | 8 (4.6) | 12 (5.0) | |
| Southwest | 25 (4.8) | 6 (3.5) | 13 (5.4) | |
| Northwest | 28 (5.4) | 10 (5.8) | 11 (4.6) | |
| Income | High | 249 (48.3) | 76 (43.9) | 100 (41.7) |
| Medium and below | 267 (51.7) | 97 (56.1) | 140 (58.3) | |
| Body mass index | Non-obese | 342 (66.3) | 97 (56.1) | 136 (56.7) |
| Obesity | 174 (33.7) | 76 (43.9) | 104 (43.3) | |
| Marriage | Single | 246 (47.7) | 89 (51.4) | 114 (47.5) |
| Married | 254 (49.2) | 75 (43.4) | 116 (48.3) | |
| Divorced | 12 (2.3) | 6 (3.5) | 6 (2.5) | |
| Widowed | 4 (0.8) | 3 (1.7) | 4 (1.7) | |
| Smoking or drinking habits | Addicted | 96 (18.6) | 36 (20.8) | 40 (16.7) |
| Not addictive | 420 (81.4) | 137 (79.2) | 200 (83.3) | |
| History of allergic diseases | Yes | 263 (51.0) | 85 (49.1) | 129 (53.8) |
| No | 253 (49.0) | 88 (50.9) | 111 (46.3) | |
| Family history | Yes | 155 (30.0) | 49 (28.3) | 66 (27.5) |
| No | 361 (70.0) | 124 (71.7) | 174 (72.5) | |
| Years of illness | <1 | 88 (17.1) | 29 (16.8) | 40 (16.7) |
| 1-3 | 175 (33.9) | 63 (36.4) | 77 (32.1) | |
| 4-10 | 139 (26.9) | 42 (24.3) | 62 (25.8) | |
| >10 | 114 (22.1) | 39 (22.5) | 61 (25.4) | |
| Allergen | Seasonal | 332 (64.3) | 110 (63.6) | 142 (59.2) |
| Annual | 184 (35.7) | 63 (36.4) | 98 (40.8) | |
| Duration of symptoms | Intermittent | 251 (48.6) | 73 (42.2) | 110 (45.8) |
| Persistent | 265 (51.4) | 100 (57.8) | 130 (54.2) | |
| Severity of illness | Mild | 286 (55.4) | 86 (49.7) | 130 (54.2) |
| Medium-severe | 230 (44.6) | 87 (50.3) | 110 (45.8) | |
| Total | 516 (100.0) | 173 (100.0) | 240 (100.0) |
Table 2 TCM constitution distribution in anxiety/depression
| TCM Constitution | Anxiety | Depression | Total |
|---|---|---|---|
| Balanced | 3 (1.7) | 5 (2.0) | 101 (19.6) |
| Qi-deficiency | 13 (7.5) | 17 (7.0) | 24 (4.7) |
| Yang-deficiency | 41 (23.7) | 64 (26.7) | 114 (22.1) |
| Yin-deficiency | 6 (3.5) | 8 (3.3) | 23 (4.4) |
| Phlegm-dampness | 30 (17.3) | 37 (15.4) | 58 (11.2) |
| Dampness-heat | 13 (7.5) | 19 (8.0) | 47 (9.1) |
| Blood-stasis | 2 (1.1) | 7 (3.0) | 15 (2.9) |
| Qi-stagnation | 17 (9.8) | 22 (9.2) | 27 (5.2) |
| Inherited-special | 48 (27.7) | 61 (25.4) | 107 (20.7) |
| Total | 173 (100.0) | 240 (100.0) | 516 (100.0) |
| P value | ﹤0.001a | ﹤0.001b | ﹤0.001c |
Table 2 TCM constitution distribution in anxiety/depression
| TCM Constitution | Anxiety | Depression | Total |
|---|---|---|---|
| Balanced | 3 (1.7) | 5 (2.0) | 101 (19.6) |
| Qi-deficiency | 13 (7.5) | 17 (7.0) | 24 (4.7) |
| Yang-deficiency | 41 (23.7) | 64 (26.7) | 114 (22.1) |
| Yin-deficiency | 6 (3.5) | 8 (3.3) | 23 (4.4) |
| Phlegm-dampness | 30 (17.3) | 37 (15.4) | 58 (11.2) |
| Dampness-heat | 13 (7.5) | 19 (8.0) | 47 (9.1) |
| Blood-stasis | 2 (1.1) | 7 (3.0) | 15 (2.9) |
| Qi-stagnation | 17 (9.8) | 22 (9.2) | 27 (5.2) |
| Inherited-special | 48 (27.7) | 61 (25.4) | 107 (20.7) |
| Total | 173 (100.0) | 240 (100.0) | 516 (100.0) |
| P value | ﹤0.001a | ﹤0.001b | ﹤0.001c |
| 1. | Brożek JL, Bousquet J, Agache I, et al. Allergic rhinitis and its impact on asthma (ARIA) guidelines-2016 revision J Allergy Clin Immunol 2017; 140: 950-8. |
| 2. |
Kuo HC, Chang LS, Tsai ZY, Wang LJ. Allergic diseases do not impair the cognitive development of children but do damage the mental health of their caregivers. Sci Rep 2020; 10: 13854.
DOI |
| 3. |
Sutcliffe JH, Greenberger PA. Identifying psychological difficulties in college athletes. J Allergy Clin Immunol Pract 2020; 8: 2216-9.
DOI PMID |
| 4. |
Fereidouni M, Rezapour H, Saharkhiz M, et al. A study of the association of cognitive abilities and emotional function with allergic disorders in young women. BMC Womens Health 2021; 21: 205.
DOI PMID |
| 5. |
Kim SY, Choi SH, Kim JD, et al. Korean youth with comorbid allergic disease and obesity show heightened psychological distress. J Pediatr 2019; 206: 99-104.
DOI URL |
| 6. |
Burrows AG, Ellis AK. Psychological impacts of coronavirus disease 2019 on people with asthma, allergic rhinitis, and food allergy. Ann Allergy Asthma Immunol 2022; 129: 52-61.
DOI URL |
| 7. | Collaborators GDaIIaP. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018;392: 1789-858. |
| 8. |
Ferrari AJ, Charlson FJ, Norman RE, et al. Burden of depressive disorders by country, sex, age, and year: findings from the global burden of disease study 2010. PLoS Med 2013; 10: e1001547.
DOI URL |
| 9. |
Steel Z, Marnane C, Iranpour C, et al. The global prevalence of common mental disorders: a systematic review and Meta-analysis 1980-2013. Int J Epidemiol 2014; 43: 476-93.
DOI PMID |
| 10. | Collaborators GDaIIaP. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet 2016; 388: 1545-602. |
| 11. | Wang Q. Individualized medicine, health medicine, and constitutional theory in Chinese medicine. Front Med 2012; 6: 1-7. |
| 12. |
Li LR, Wang ZY, Wang J, Zheng YF, Li YS, Wang Q. Enlightenment about using TCM constitutions for individualized medicine and construction of Chinese-style precision medicine: research progress with TCM constitutions. Sci China Life Sci 2021; 64: 2092-9.
DOI PMID |
| 13. |
Liang X, Wang Q, Jiang ZQ, et al. Clinical research linking Traditional Chinese Medicine constitution types with diseases: a literature review of 1639 observational studies. J Tradit Chin Med 2020; 40: 690-702.
DOI PMID |
| 14. |
Wang J, Yu RX, Wang Q. New concept of health with perspective of Chinese Medicine. Chin J Integr Med 2019; 25: 712-5.
DOI PMID |
| 15. | Medicine CAoC. Classification and judgment standards of Traditional Chinese Medicine constitution. Shi Jie Zhong Xi Yi Jie He Za Zhi 2009; 4: 303-4. |
| 16. | Qu S, Qu SL.Diagnostic test of screening generalized anxiety disorders in general hospital psychological department with GAD-7. Zhong Guo Xin Li Wei Sheng Za Zhi 2015; 23: 939-44. |
| 17. | Qu S, Shi XX, Xie ZJ, Ding RJ, Zheng MJ. Validity and reliability of the patient health questionnaire and the generalized anxiety scale for screening depressive anxiety in patients with non-cardiac chest pain. Zhong Guo Xin Li Wei Sheng Za Zhi 2021; 35: 376-81. |
| 18. | Concato J, Feinstein AR. Monte Carlo methods in clinical research: applications in multivariable analysis. J Investig Med 1997; 45: 394-400. |
| 19. | Bai MH, Wang J, Zheng YF, et al. Analysis of distribution characteristics of TCM body constitution types in Chinese population based on data of 108 015 cases. Beijing Zhong Yi Yao Da Xue Xue Bao 2020; 43: 498-507. |
| 20. | Sun PC, Wang J, Yang PY, Wang Q. Study on identification and intervention of composite constitutions. Beijing Zhong Yi Yao Da Xue Xue Bao 2019; 42: 99-102. |
| 21. | Wang YQ, Luo B, Zhao WB, Chen BT, Wang J. Distribution of TCM constitution types of 177 patients with allergic rhinitis and its correlation with anxiety and depression. Beijing Zhong Yi Yao Da Xue Xue Bao 2021; 43: 544-9. |
| 22. | Zhao WB, Wang YQ, Zhao HH, et al. Analysis on Traditional Chinese Medicine particular (allergic) constitution related diseases’ prevention and treatment thinking. Zhong Hua Zhong Yi Yao Za Zhi 2022; 37: 4499-502. |
| 23. |
Wang J, Wang T, Li YS, Li LR, Zheng YF, Wang Q. Allergic constitution theory of Chinese medicine and its assessment criterion and related studies. Chin J Integr Med 2015; 21: 716-20.
DOI PMID |
| 24. |
Li Q, Zhang X, Feng Q, et al. Common allergens and immune responses associated with allergic rhinitis in China. J Asthma Allergy 2023; 16: 851-61.
DOI PMID |
| 25. |
Kaczkurkin AN, Raznahan A, Satterthwaite TD. Sex differences in the developing brain: insights from multimodal neuroimaging. Neuropsychopharmacology 2019; 44: 71-85.
DOI PMID |
| 26. | Brébion G, Núñez C, Lombardini F, et al. Subclinical depression and anxiety impact verbal memory functioning differently in men and women -an fMRI study. J Psychiatr Res 2021; 140: 308-15. |
| 27. | Shyam S, Gómez-Martínez C, Paz-Graniel I, et al. Coronavirus disease 2019 is associated with long-term depressive symptoms in Spanish older adults with overweight/obesity and metabolic syndrome. Psychol Med 2023: 1-11. |
| 28. |
Zhao X, Davey G, Wan X. Interplay of depression, smoking intention, and smoking behavior in Chinese Dai adolescents. J Addict Nurs 2023; 34: 211-5.
DOI URL |
| 29. | Osundolire S, Goldberg RJ, Lapane KL. Anxiety and depression among US nursing home residents with chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 2023; 18: 1867-82. |
| 30. | Kelly RC, Holt RIG, Desborough L, et al. The psychosocial burdens of living with diabetes. Diabet Med 2023; 3: e15219. |
| 31. | Tian W, Zhang Y, Han X, et al. Development and validation of a predictive model for depression risk in the U.S. adult population: Evidence from the 2007-2014 NHANES. BMC Psychol 2023; 11: 244. |
| 32. |
Villalobos BT, Hernandez Rodriguez J. How did Latinxs near the U.S.-Mexico border fare during the COVID-19 pandemic? A snapshot of anxiety, depression, and posttraumatic stress symptoms. Front Psychol 2023; 14: 1241603.
DOI URL |
| 33. |
Lo HKY, Chan JKN, Yip EWC, et al. The prevalence and correlates of suicidal ideation in Chinese psychiatric patients during the fifth wave of COVID-19 in Hong Kong. Eur Neuropsychopharmacol 2023; 77: 4-11.
DOI PMID |
| 34. |
Ariaratnam S, Kee CC, Krishnapillai AD, et al. Smoking status and its relationship with depression among the elderly population in Malaysia: findings from the National Health and Morbidity Survey 2018. Tob Induc Dis 2023; 21: 109.
DOI PMID |
| 35. | Zhang XC, Zhang XQ, Yang T, Zhang H. Relationship between Chinese Medicine Constitution an depression of 671 college students in Nanjing. Nanjing Zhong Yi Yao Da Xue Xue Bao 2019; 20: 245-9. |
| 36. | He FL, Guo Q, Yang L, Ren XJ, Ye YJ. Relationship between anxiety, depression and Traditional Chinese Medicine constitution in patients with metabolic syndrome. Shi Jie Zhong Xi Yi Jie He Za Zhi 2022; 17: 1655-8. |
| 37. |
Kong Q, Chen LM, Dai ZH, et al. Care patterns and Traditional Chinese Medicine constitution as factors of depression and anxiety in patients with systemic sclerosis: a cross-sectional study during the COVID-19 pandemic. Front Integr Neurosci 2023; 17: 1052683.
DOI URL |
| 38. | Yap SY, Ng FL, Subramaniam M, Lim YM, Foo CN. Traditional Chinese Medicine body constitutions as predictors for depression: a systematic review and Meta-analysis. Behav Sci (Basel) 2022; 12: 423. |
| 39. |
Liao YC, Chou CY, Chang CT, et al. Qi deficiency is associated with depression in chronic hemodialysis patients. Complement Ther Med 2017; 30: 102-6.
DOI URL |
| 40. |
Chen SL, Liu YT, Hsueh KC, Tang PL. Body constitution of Traditional Chinese Medicine caused a significant effect on depression in adult women. Complement Ther Clin Pract 2021; 42: 101288.
DOI URL |
| 41. |
Wilson JB, Epstein M, Lopez B, Brown AK, Lutfy K, Friedman TC. The role of neurochemicals, stress hormones and immune system in the positive feedback loops between diabetes, obesity and depression. Front Endocrinol (Lausanne) 2023; 14: 1224612.
DOI URL |
| 42. | Lü HP, Wang TF, Wu XY, et al. Correlation between nine body constitutions in TCM and mental health among enrolled students based on Symptom Checklist 90. Beijing Zhong Yi Yao Da Xue Xue Bao 2022; 45: 941-8. |
| 43. |
Huang H, Song Q, Chen J, et al. The role of Qi-stagnation constitution and emotion regulation in the association between childhood maltreatment and depression in Chinese college students. Front Psychiatry 2022; 13: 825198.
DOI URL |
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