Journal of Traditional Chinese Medicine >
Acupuncture with different frequencies for tobacco dependence: a randomized controlled trial
Received date: 2023-05-20
Accepted date: 2023-11-30
Online published: 2024-09-27
Supported by
Fund of Science and Technology Innovation Project of Chinese Academy of Chinese Medical Sciences Project: Self-service Acupuncture Smoking Cessation Research and Development(CI2021A03506);Fund of Capital Health Development Special Research Project: Research on Development and Clinical Applicalion of Wrist Acupuncture Smoking Cessation Instrument(2022-1-4281)
OBJECTIVE: To observe the effect of different acupuncture frequencies on the abstinence rate which could be used as a reference for optimizing acupuncture cessation programs.
METHODS: From July 2018 to June 2022, a total of 220 smokers were recruited based on inclusion criteria and randomly divided into the high-frequency acupuncture group (HF group, n = 110): 5 times a week from the 1st to the 4th week, from weeks 5 to 8, three times a week and the low-frequency acupuncture group (LF group, n = 110): 3 times a week from the 1st to the 4th week, from weeks 5 to 8, twice a week, then treated for 8 weeks and follow-up at 1 month in Beijing.
RESULTS: In total, 162 subjects completed the whole study with a drop-out rate of 20.45%. The expiratory CO point abstinence rate was HF group 53/110 (48.18%) vs LF group 41/110 (37.27%) in Week 8 (P = 0.102) and HF group 46/110 (41.82%) vs LF group 45/110 (40.91%) in Week 12 (P = 0.891) and the HF acupuncture and LF acupuncture were nearly equal in the 8-week abstinence rate. In addition, both HF and LF acupuncture significantly reduced Fagerstrőm test for nicotine dependence scale (FTND) scores (P < 0.05), Minnesota nicotine withdrawal scale (MNWS) scores (P < 0.05), and Brief Questionnaire of Smoking Urges scale (QSU-Brief) scores (P < 0.05), but HF acupuncture showed some superiority over LF acupuncture in relieving patients' smoking cravings (P < 0.05).
CONCLUSIONS: The study initially showed that both high-frequency acupuncture and low-frequency acupuncture treatment were safe and effective on smoking cessation for 8 weeks, but high-frequency acupuncture was advantageous in reducing smoking cravings. More accurate acupuncture frequency needs to be validated through larger clinical studies to optimize acupuncture smoking cessation programs.
Key words: acupuncture; acupuncture frequency; tobacco dependence; smoking cessation
Shumin CHEN , Zhenyu LIU , Jia JI , Jin CHANG , Zhihua LI , Yingying WANG , Jinsheng YANG . Acupuncture with different frequencies for tobacco dependence: a randomized controlled trial[J]. Journal of Traditional Chinese Medicine, 2025 , 45(3) : 651 -659 . DOI: 10.19852/j.cnki.jtcm.2025.03.022
| 1. | Fouad H, Commar A, Hamadeh R, El-Awa F, Shen Z, Fraser C. Estimated and projected prevalence of tobacco smoking in males, eastern mediterranean region, 2000-2025. East Mediterr Health J 2021; 27: 76-82. |
| 2. | Rigotti NA, Kruse GR, Livingstone-Banks J, Hartmann-Boyce J. Treatment of tobacco smoking: a review. JAMA 2022; 327: 566-77. |
| 3. | Ministry of Health of People’s Republic of China, China Report on the Health Hazards of Smoking. Beijing: People's Medical Publishing House, 2021: 1-4. |
| 4. | Wang JH, van Haselen R, Wang M, et al. Acupuncture for smoking cessation: a systematic review and Meta-analysis of 24 randomized controlled trials. Tob Induc Dis 2019; 4: 48. |
| 5. | Lhommeau N, Huchet A, Castera P. Acupuncture et arrêt de la consommation tabagique, unerevue de la littérature [Acupuncture and smoking cessation, a review of the literature]. Rev Mal Respir 2020; 37: 474-8. |
| 6. | Dai R, Cao Y, Zhang H, et al. Comparison between acupuncture and nicotine replacement therapies for smoking cessation based on randomized controlled trials: a systematic review and bayesian network Meta-analysis. Evid Based Complement Alternat Med 2021; 2021: 9997516. |
| 7. | Bier ID, Wilson J, Studt P, Shakleton M. Auricular acupuncture, education, and smoking cessation: a randomized, sham-controlled trial. Am J Public Health 2002; 92: 1642-7. |
| 8. | Lee EJ. The effect of auricular acupressure and positive group psychotherapy with motivational interviewing for smoking cessation in korean adults. Holist Nurs Pract 2020; 34: 113-20. |
| 9. | Dai R, Zhang J, Zhang H, Zhao N, Song F, Fan J. Effect of acupuncture and auricular acupressure on smoking cessation: protocol of a systematic review and bayesian network Meta-analysis. Medicine (Baltimore) 2020; 99: e20295. |
| 10. | Yoon DE, Lee IS, Chae Y. Identifying dose components of manual acupuncture to determine the dose-response relationship of acupuncture treatment: a systematic review. Am J Chin Med 2022; 50: 653-71. |
| 11. | Lin LL, Wang LQ, Yang JW, et al. Researches status on time-effect of acupuncture. Zhong Guo Zhen Jiu 2019; 39: 565-70. |
| 12. | FF Ma, HW Zhang, BX Li, PY Cheng, Yu MW, Wang XM. Acupuncture and moxibustion for malignant tumor patients with psychological symptoms of insomnia, anxiety and depression: a systematic review and Meta-analysis. J Tradit Chin Med 2023; 43: 441-56. |
| 13. | Liu Z, Yang JS, Wu Y, et al. Predictors for smoking cessation with acupuncture in a hong kong population. Evid Based Complement Alternat Med 2015; 2015: 189694. |
| 14. | Wang TS, Bai P. Clinical study of 37 cases of periarthritis of shoulder treated with different acupuncture frequency. Jiangsu Zhong Yi Yao 2019; 51: 62-5. |
| 15. | Eisenberg MJ, Hébert-Losier A, Windle SB, et al. Effect of e-cigarettes plus counseling vs counseling alone on smoking cessation: a randomized clinical trial. JAMA 2020; 324: 1844-854. |
| 16. | Regional Office for the Western Pacific. World health organization standard acupuncture acupoint location-western pacific region. World Health Organization 2009: 25-219. |
| 17. | Liu Z, Wang YY, Wu Y, et al. Modern literature research on acupuncture and smoking cessation. J Tradit Chin Med 2015; 56: 2116-20. |
| 18. | Jang S, Lee JA, Jang BH, Shin YC, Ko SG, Park S. Clinical effectiveness of traditional and complementary medicine interventions in combination with nicotine replacement therapy on smoking cessation: a randomized controlled pilot trial. J Altern Complement Med 2019; 25: 526-34. |
| 19. | Wee LH, West R, Mariapun J, et al. Should the threshold for expired-air carbon monoxide concentration as a means of verifying self-reported smoking abstinence be reduced in clinical treatment programmes? Evidence from a Malaysian smokers' clinic. Addict Behav 2015; 47: 74-9. |
| 20. | Chulasai P, Chinwong D, Vientong P, et al. Smartphone application for smoking cessation (quit with us): a randomized controlled trial among young adult light smokers in thailand. Int J Environ Res Public Health 2022; 19: 8265. |
| 21. | Dijkstra A, Tromp D. Is the FTND a measure of physical as well as psychological tobacco dependence? J Subst Abuse Treat 2002; 23: 367-74. |
| 22. | Whittaker R, Borland R, Bullen C, Lin RB, McRobbie H, Rodgers A. Mobile phone-based interventions for smoking cessation. Cochrane Database Syst Rev 2016; 4: CD006611. |
| 23. | Chai X, Yang JS, Liu Z, et al. Effect of the different smoking cessation regimens with acupuncture on smoking withdrawal and their influence factors: a multi-center randomized controlled trial. Zhong Guo Zhen Jiu 2019; 39: 1255-261. |
| 24. | Wang YY, Liu Z, Wu Y, et al. Efficacy of acupuncture is noninferior to nicotine replacement therapy for tobacco cessation: results of a prospective, randomized, active-controlled open-label trial. Chest 2018; 153: 680-88. |
| 25. | Wang YY, Liu Z, Wu Y, et al. A randomized controlled trial on smoking cessation by acupuncture. Beijing Zhong Yi Yao Da Xue Xue Bao 2018; 41: 605-10. |
| 26. | Hajek P, Phillips-Waller A, Przulj D, et al. A randomized trial of e-cigarettes versus nicotine-replacement therapy. N Engl J Med 2019; 380: 629-37. |
| 27. | Quisenberry AJ, Pittman J, Goodwin RD, Bickel WK, D'Urso G, Sheffer CE. Smoking relapse risk is increased among individuals in recovery. Drug Alcohol Depend 2019; 202: 93-103. |
| 28. | Fagerstr?m K, Russ C, Yu CR, Yunis C, Foulds J. The Fagerstr?m test for nicotine dependence as a predictor of smoking abstinence: a pooled analysis of varenicline clinical trial data. Nicotine Tob Res 2012; 14: 1467-73. |
| 29. | Liu Z, Wang YY, Wu Y, et al. Analysis of compliance factors of subjects with acupuncture smoking cessation in Hong Kong. Beijing Zhong Yi Yao Da Xue Xue Bao 2016; 39: 82-8. |
| 30. | Biedermann F, Fleischhacker WW. Psychotic disorders in DSM-5 and ICD-11. CNS Spectr 2016; 21: 349-54. |
| 31. | Fei YT, Cao HJ, Xia RY, et al. Methodological challenges in design and conduct of randomised controlled trials in acupuncture. BMJ 2022; 376: e064345. |
| 32. | Yuan YY, Zhang W, Kuang HJ, et al. Literature study on clinical outcome indicators in randomized controlled trials of acupuncture and smoking cessation. Zhong Yi Za Zhi 2022; 63: 1179-185. |
| 33. | Chen Q, Wang Q, Ding S, et al. Problems lowering the study quality in traditional medicine, introspection from an example of Meta-analysis of acupuncture. BMC Complement Med Ther 2020; 20: 41. |
| 34. | Besson M, Granon S, Mameli-Engvall M, et al. Long-term effects of chronic nicotine exposure on brain nicotinic receptors. Proc Natl Acad Sci USA 2007; 104: 8155-60. |
| 35. | Jin YT, Wu LT, Guo YL, Xia C, Yu BY, Xuan LH. Long-term efficacy of point application therapy on different acupoints and durations in the treatment of asthma: a randomized controlled trial. J Tradit Chin Med 2023; 43: 146-53. |
| 36. | Leone FT, Zhang Y, Evers-Casey S, et al. Initiating pharmacologic treatment in tobacco-dependent adults. An official american thoracic society clinical practice guideline Am J Respir Crit Care Med 2020; 202: e5-31. |
| 37. | Yavagal PC, Nagesh L. Efficacy of laser auricular acupuncture for smoking cessation: a randomised controlled trial. Sultan Qaboos Univ Med J 2021; 21: e275-81. |
| 38. | Hugley MJ, Wolford-Clevenger C, Sisson ML, Nguyen AT, Cropsey KL. Self-initiated gradual smoking reduction among community correction smokers. Addict Behav 2019; 93: 100-3. |
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