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Journal of Traditional Chinese Medicine >

2022 , Vol. 42 >Issue 2: 242 - 249

DOI: https://doi.org/10.19852/j.cnki.jtcm.20211214.003

Research Articles

Ginger-indirect moxibustion plus acupuncture versus acupuncture alone for chronic fatigue syndrome: a randomized controlled trial

  • Tingting MA ,
  • Jie WU ,
  • Lijie YANG ,
  • Fen FENG ,
  • Huilin YANG ,
  • Jinhua ZHANG ,
  • Yanjin ZHONG ,
  • Qing NING ,
  • Lirong HUANG ,
  • Youbing LIN ,
  • Jue YAN ,
  • Guiquan CHEN ,
  • Tianshu HOU ,
  • Li WANG ,
  • Yuanfang REN ,
  • Jing TAN
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  • 1 Center of Preventive Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China
    2 College of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China
    3 Department of acupuncture, Center of Preventive Medicine, Affiliated TCM Hospital of Southwest Medical University, Luzhou 646600, China
    4 Center of Preventive Medicine, Chengdu Integrated TCM and Western Medicine Hospital, Chengdu 610021, China
    5 Center of Chinese Evidence-Based Medicine, Sichuan University West China Hospital, Chengdu 610041, China
WU Jie, Center of Preventive Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China. drwujie@163.com, Telephone: +86-028-87783128

Received date: 2021-05-16

  Accepted date: 2021-08-22

  Online published: 2021-12-14

Supported by

Science and Technology Support Program of Sichuan Province Science and Technology Agency: Clinical Researches of Acupuncture for “Unhealthy Status” Based on the TCM Theory of “All Diseases Originate from Qi’s Problem”(2014SZ0152)

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Abstract

OBJECTIVE: To assess the efficacy and safety of ginger-indirect moxibustion for chronic fatigue syndrome (CFS).

METHODS: In this central randomized, controlled trial, 290 CFS participants were recruited and randomly allocated to group A (ginger-indirect moxibustion plus acupuncture) or group B (acupuncture alone). The study consisted of a treatment period of 8 weeks with a total of 24 treatments (3 sessions per week, every other day), and a follow-up period of 12 weeks. The outcome was measured by Fatigue Severity Scale (FSS), Psychological Health Report (SPHERE), the Self-rating depression scale (SDS) and the Hamilton anxiety scale (HAMA) at baseline, 2, 4, 6, 8, 12 and 20 weeks.

RESULTS: With the treatment undergoing, the changes of FSS, SPHERE, SDS and HAMA scores in both groups increased gradually, and the effect maintained at the 12th week. Between groups, significantly higher score changes were seen in group A in FSS after 4 weeks treatment (11.94 vs 9.12, 95%CI: 0.94, 4.7) and in SPHERE after 2 weeks treatment (3.7 vs 2.27, 95%CI: 0.56, 2.31). But for SDS and HAMA, the improvement did not differ significantly between groups. No severe adverse events were reported.

CONCLUSION: Ginger-indirect moxibustion is a safe and effective intervention to relieve fatigue and accompanying physical symptoms of CFS.

Key words： ginger-indirect moxibustion; fatigue syndrome, chronic; treatment outcome; safety; randomized controlled trial

Cite this article

Tingting MA , Jie WU , Lijie YANG , Fen FENG , Huilin YANG , Jinhua ZHANG , Yanjin ZHONG , Qing NING , Lirong HUANG , Youbing LIN , Jue YAN , Guiquan CHEN , Tianshu HOU , Li WANG , Yuanfang REN , Jing TAN . Ginger-indirect moxibustion plus acupuncture versus acupuncture alone for chronic fatigue syndrome: a randomized controlled trial[J]. Journal of Traditional Chinese Medicine, 2022 , 42(2) : 242 -249 . DOI: 10.19852/j.cnki.jtcm.20211214.003

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