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Journal of Traditional Chinese Medicine ›› 2021, Vol. 41 ›› Issue (4): 499-506.DOI: 10.19852/j.cnki.jtcm.20210220.003

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Clinical effects of the combination of Traditional Chinese and Western Medicines on coronavirus disease 2019: a systematic review and Meta-analysis

YAN Lizhao, MAO Fuwei, CAO Yinghao, XIE Mao   

  1. Department of Hand Surgery,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology;Department of Gastrointestinal Surgery,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology;Department of Orthopaedic Surgery,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology;
  • Online:2021-08-06 Published:2021-08-06
  • Supported by:
    Supported by the Graduates'Innovation Fund,Huazhong University of Science and Technology (No. 2020yjs CXCY055), Free Innovation Pre-research Fund and Platform Scientific Research Fund in 2019 (No. 02.03.2019-111)

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Abstract: OBJECTIVE: To explore the clinical efficacy of the combination of Traditional Chinese and Western Medicines for the treatment of coronavirus disease2019(COVID-19).METHODS: Studies were identified in six popular medical databases.RESULTS: Thirteen studies were included. The results showed that combined treatment with Traditional Chinese and Western Medicines can reduce the probability of progression from mild to severe disease [RR = 0.34, 95% confidence interval(CI)(0.18, 0.65)](P = 0.001) and improve the clinical cure rate [RR = 0.17, 95% CI(0.05, 0.28)](P = 0.004).The use of an integrated treatment strategy shortened the time to the remission of fever [WMD =-1.27, 95% CI(-1.67,-0.92)](P < 0.001) and improved the incidences of the disappearance of fever and fatigue [RR = 1.25, 95% CI(1.06, 1.47)(P =0.007); RR = 1.49, 95% CI(1.13, 1.97)(P = 0.004)].CONCLUSION: A combined treatment strategy is effective for COVID-19.

Key words: COVID-19, severe acute respiratory syndrome, herbal medicine, systematic review, Meta-analysis

Cite this article

YAN Lizhao, MAO Fuwei, CAO Yinghao, XIE Mao. Clinical effects of the combination of Traditional Chinese and Western Medicines on coronavirus disease 2019: a systematic review and Meta-analysis[J]. Journal of Traditional Chinese Medicine, 2021, 41(4): 499-506.