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Journal of Traditional Chinese Medicine ›› 2018, Vol. 38 ›› Issue (05): 746-753.

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Mixture prepared with Chinese medicines in terms of releasing exterior cold and clearing interior heat: its efficacy and safety in patients with seasonal influenza-a randomized controlled trial

Wu Zhisong, Li Guodong, Wei Wan, Liu Zhaoheng, Wang Wei, Ma Ruihong, Liu Wenhong, Ma Jiaju, Wang Yuguang, Jiao Yang   

  1. Department of Intensive care unit, Dongfang Hospital Affiliated to Beijing University of Chinese Medicine;Graduate School, Beijing University of Chinese Medicine;Department of Chinese Medicine, Concord Hospital Affiliated to Fujian Medical University;Department of Respiratory medicine, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University;Department of Internal Medicine, Dongfang Hospital Affiliated to Beijing University of Chinese Medicine;
  • Online:2018-10-15 Published:2018-10-15
  • Supported by:
    Supported by National Science and Technology Support Program:Research on unique treatment and principle of inheritance famous old traditional Chinese doctors(No.2013BAI13B021), The Beijing municipal administration of traditional Chinese medicine inheriting program:workstation of famous doctor Zhou Ping-an construction project, The Innovative Team Project of Beijing University of Chinese Medicine(No.2011-CXTD-08)

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Abstract: OBJECTIVE: To assess the efficacy and safety in 105 patients with seasonal Influenza in Beijing, the mixture prepared with Chinese medicines follows the treatment regimen of releasing exterior cold andclearing interior heat.METHODS: Total 330 patients with seasonal influenza were enrolled and randomly and averagely divided into the Chinese herbal medicine, the western medicine and the Chinese patent medicine group. They were treated with Chinese medicine Oseltamivir Phosphate Capsules and the Scattering Wind and Resolving Toxins Capsules. The main efficacy indicators were the antifebrile onset time and recovery time of body temperature. The efficacy and safety of the mixture was scientifically evaluated. Comparisons of several variables were analyzed.RESULTS: Median antifebrile onset time of the Chinese herbal medicine group was significantly shorter than the western medicine group(P < 0.05) and the Chinese patent medicine group(P < 0.05). The median antifebrile recovery time of the Chinese herbal medicine group was significantly shorter than the Chinese patent medicine group(P

Key words: Releasing exterior cold and clearing interior heat, Influenza, efficacy, Mixture prepared with Chinese medicines

Cite this article

Wu Zhisong, Li Guodong, Wei Wan, Liu Zhaoheng, Wang Wei, Ma Ruihong, Liu Wenhong, Ma Jiaju, Wang Yuguang, Jiao Yang. Mixture prepared with Chinese medicines in terms of releasing exterior cold and clearing interior heat: its efficacy and safety in patients with seasonal influenza-a randomized controlled trial[J]. Journal of Traditional Chinese Medicine, 2018, 38(05): 746-753.