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Journal of Traditional Chinese Medicine ›› 2018, Vol. 38 ›› Issue (02): 266-271.

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Effect of Ningmitai capsule plus sertraline on patients with premature ejaculation and enlarged seminal vesicles:A randomized clinical trial

Peng Longping, Hong Zhiwei, Shen Jiaming, Hu Xuechun, Shao Yong, Jing Jun, Lu Jinchun, Yao Bing   

  1. Center for Reproductive Medicine,Jinling Hospital Affiliated to Southern Medical University;Center for Reproductive Medicine,Jinling Hospi-tal,Medical School of Nanjing University;Department of Laboratory Science,Nanjing Hospital,Jiangsu Corps,the Armed Police Force,Chinese People's Liberation Army;
  • Online:2018-04-15 Published:2018-04-15
  • Supported by:
    Supported by a Grant from the National Key Basic Research Program of China(No.2013CB945204), a Research and Development Project for Young Doctors in Reproductive Medicine from the Chinese Medical Association Specialized Fund for Clinical Medical Research(No.16020380654)

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Abstract: OBJECTIVE: To investigate the effects of Ningmitai capsule combined with sertraline on patients with premature ejaculation(PE) and an increased anterior-posterior diameter(APD) of the seminal vesicles(SVs).METHODS: Sixty men with acquired PE were enrolled and randomly divided into two groups. The combined group was treated with Ningmitai capsule and sertraline, while the control group was treated with sertraline alone. Main outcomes were measured using the premature ejaculation diagnostic tool(PEDT), APD of SVs, and Clinical Global Impression of Change questionnaire and compared before and after 3 months of treatment.RESULTS: Comparing after treatment with before treatment outcomes within each group, the PEDT score was significantly reduced in the combined group(12.1 ± 2.5 vs 8.6 ± 3.2, P < 0.001, respectively) and control group(12.9 ± 2.6 vs 10.3 ± 1.6, P

Key words: Premature ejaculation, Seminal vesicles, Therapeutics, Ningmitai capsule, Randomized clinical trials

Cite this article

Peng Longping, Hong Zhiwei, Shen Jiaming, Hu Xuechun, Shao Yong, Jing Jun, Lu Jinchun, Yao Bing. Effect of Ningmitai capsule plus sertraline on patients with premature ejaculation and enlarged seminal vesicles:A randomized clinical trial[J]. Journal of Traditional Chinese Medicine, 2018, 38(02): 266-271.