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Journal of Traditional Chinese Medicine ›› 2012, Vol. 32 ›› Issue (02): 164-172.DOI: 10.1016/s0254-6272(13)60006-0

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A clinical study of Weining Granules in the treatment of gastric precancerous lesions

Deng Xin , Liu Zhen Wei , Wu Fa Sheng , Li Long Hua , Liang Jian   

  1. Guangxi Traditional Chinese Medical University;The First Hospital,Jiangxi University of Traditional Chinese Medicine;
  • Accepted:2012-06-15 Online:2012-06-15 Published:2012-06-15

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Abstract: OBJECTIVE:To investigate the clinical effects of Weining Granules on gastric precancerous lesions(GPLs).METHODS:120 patients with GPLs were randomly assigned in a 1:1 ratio to receive Weining Granules(trial group) or the comparator Weifuchun tablets(control group) for 6 months.Outcomes were compared between the two groups including:overall response;gastroscopically-determined response;pathologically-confirmed response;eradication of Helicobacter pylori(HP);microvessel density(MVD) in the gastric mucosa;expression of vascular endothelial growth factor(VEGF);interleukin 2(IL-2);interleukin 6(IL-6);T lymphocyte subsets;immunoglobulins;symptom scores;quality of life(QOL);and adverse reactions.RESULTS:Patients in the trial group had a significantly higher(P

Key words: Gastric precancerous lesions, Weining Granules, Weifuchun Tablets, Clinical study

Cite this article

Deng Xin , Liu Zhen Wei , Wu Fa Sheng , Li Long Hua , Liang Jian. A clinical study of Weining Granules in the treatment of gastric precancerous lesions[J]. Journal of Traditional Chinese Medicine, 2012, 32(02): 164-172.