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Journal of Traditional Chinese Medicine ›› 2022, Vol. 42 ›› Issue (5): 833-838.DOI: 10.19852/j.cnki.jtcm.2022.05.011

• Research Articles • Previous Articles    

Application value of Qisexingtai hand diagnostic method in diagnosis of coronary artery disease

LIU Qian1, ZHAO Zhupei1(), GUO Hua2, WANG Shiheng1, HAO Mingzhao1, QIN Peijie1, WANG Liuqing1, LIU Xuechun1, ZHANG Fengxia1, AN Hong1, LI Yu1, SHI Xueqin1, ZHU Tingyu1, LIU Jianfeng1(), WANG Liying3, XU Tao4, ZHANG Limei5, ZOU Xu6   

  1. 1 Institute for the History of Chinese Medicine and Medical Literature, China Academy of Chinese Medical Sciences, Beijing 100700, China
    2 Graduate School of China Academy of Chinese Medical Sciences, Beijing 100700, China
    3 Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China
    4 China Chest Pain Center, The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guizhou 550003, China
    5 Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China
    6 Department of Cardiovascular Diseases, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, China
  • Received:2022-02-11 Accepted:2022-06-13 Online:2022-10-15 Published:2022-09-02
  • Contact: ZHAO Zhupei,LIU Jianfeng
  • About author:ZHAO Zhupei, Institute for the History of Chinese Medicine and Medical Literature, China Academy of Chinese Medical Sciences, Beijing 100700, China. Zhaoshupei6227@qq.com
    Dr. LIU Jianfeng, Institute for the History of Chinese Medicine and Medical Literature, China Academy of Chinese Medical Sciences, Beijing 100700, China. doctor_ljf@hotmail.com;
  • Supported by:
    National Key R&D Program of China-Study on Operating Principles of Screening, Evaluation, Promotion and Application for Diagnosis and Treatment Technology of Characteristic Folk Traditional Chinese Medicine(2019YFC1708400)

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Abstract:

OBJECTIVE: To evaluate the diagnostic efficacy of Qisexingtai hand diagnostic method in the diagnosis of coronary artery disease (CAD).

METHODS: This was an investigator-initiated, prospective, multi-center, cross-sectional study. All the participants from three hospitals in China had been diagnosed by both Qisexingtai hand diagnostic method and coronary angiography. We compared the two diagnostic methods to calculate the sensitivity, the specificity, the omission diagnostic rate, the mistaken diagnostic rate and accuracy in order to evaluate the diagnostic efficacy of Qisexingtai hand diagnostic method for CAD.

RESULTS: A total of 326 subjects were enrolled, diagnosed by both Qisexingtai hand diagnostic method and coronary angiography. As a result, there were 166 positive cases according to Qisexingtai hand diagnostic method, and 131 positive cases according to coronary angiography. Compared with the results of coronary angiography, the sensitivity of Qisexingtai hand dia-gnostic method was 80.2%, the specificity was 68.7%, the omission diagnostic rate was 19.8%, the mistaken diagnostic rate was 31.3%, and the accuracy was 73.3%. Area under the receiver operating characteristic curve was estimated as 0.735 for all, and 0.718, 0.735, 0.783 for the three sub-centers.

CONCLUSION: Qisexingtai hand diagnostic method with high accuracy and sensitivity has certain application value in the diagnosis of CAD.

Key words: hand diagnosis, coronary artery disease, diagnostic tests, routine, Qisexingtai

Cite this article

LIU Qian, ZHAO Zhupei, GUO Hua, WANG Shiheng, HAO Mingzhao, QIN Peijie, WANG Liuqing, LIU Xuechun, ZHANG Fengxia, AN Hong, LI Yu, SHI Xueqin, ZHU Tingyu, LIU Jianfeng, WANG Liying, XU Tao, ZHANG Limei, ZOU Xu. Application value of Qisexingtai hand diagnostic method in diagnosis of coronary artery disease[J]. Journal of Traditional Chinese Medicine, 2022, 42(5): 833-838.