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Journal of Traditional Chinese Medicine >

2026 , Vol. 46 >Issue 3: 706 - 714

DOI: https://doi.org/10.19852/j.cnki.jtcm.2026.03.010

Original Articles

Clinical characteristics of adolescents and young adults with type 2 diabetes and Traditional Chinese Medicine therapies: a single-center experience in China from 2011 to 2023

  • WU Jing ,
  • WANG Le ,
  • GUO Xiangyu ,
  • GAO Kuo ,
  • LIU Jinmin
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  • 1 Department of Endocrinology, Dongfang Hospital Beijing University of Chinese Medicine, Beijing 100071, China
    2 School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China
    3 Department of Neurosurgery, Dongzhimen Hospital Beijing University of Chinese Medicine, Beijing 100010, China
GAO Kuo, School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China. gk@bucm.edu.cn;
LIU Jinmin, Department of Neurosurgery, Dongzhimen Hospital Beijing University of Chinese Medicine, Beijing 100010, China. jmvip@vip.163.com, Telephone: +86-10-67689769

Received date: 2025-01-12

  Accepted date: 2025-06-30

  Online published: 2026-06-08

Supported by

Fundamental Research Funds for the Central Universities: Study on the Mechanism of Chaibei Zhixian Decoction in Treating Refractory Epilepsy through the Nitric Oxide Synthase- Reactive Oxygen Species-Ferroptosis Pathway(2025-JYB-XJSJJ041)

Fold

Abstract

OBJECTIVE: To clarify the clinical characteristics of type 2 diabetes in adolescents and young adults (T2DMY) patients, and their treatment strategies involving Traditional Chinese Medicine (TCM) and Western Medicine.

METHODS: This study was conducted at Dongfang Hospital of Beijing University of TCM. Clinical data of outpatients and inpatients from 2011 to 2023 were retrieved from the electronic medical record database with type 2 diabetes mellitus (T2DM) as the first diagnosis.

RESULTS: A total of 405 outpatients and 570 inpatients with T2DMY were included in the analysis. Compared with middle aged and elderly T2DM patients (T2DME), T2DMY patients have a higher proportion of diabetes family history and higher body mass index, poorer control of blood glucose, blood lipid, liver and kidney function, and a higher incidence of non-alcoholic fatty liver disease and gout. In terms of anti-diabetes treatment, T2DMY patients are more likely to receive metformin and insulin drugs. In terms of TCM diagnosis and treatment, compared with T2DME patients, T2DMY patients are more frequently diagnosed with the syndrome of phlegm damp trapped spleen, and more herbs such as Fuling (Poria) and Chenpi (Pericarpium Citri Reticulatae) are more frequently used to invigorate the spleen and dispel dampness.

CONCLUSION: Compared with T2DME patients, T2DMY patients have worse metabolism. In the treatment of TCM, more attention can be paid to the function of the spleen, and the herbal medicine can be used to enhance the function of the spleen and dispell dampness when it is compatible with Qitonifying drugs.

Key words： hypoglycemic agents; diabetes mellitus, type 2; adolescent; young adult; phlegm damp trapped spleen

Cite this article

WU Jing , WANG Le , GUO Xiangyu , GAO Kuo , LIU Jinmin . Clinical characteristics of adolescents and young adults with type 2 diabetes and Traditional Chinese Medicine therapies: a single-center experience in China from 2011 to 2023[J]. Journal of Traditional Chinese Medicine, 2026 , 46(3) : 706 -714 . DOI: 10.19852/j.cnki.jtcm.2026.03.010

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