Systematic Reviews

Multiple acupuncture and moxibustion therapies for allergic rhinitis in adults: a network Meta-analysis of randomized controlled trials

  • Lixia LIN ,
  • Xin LI ,
  • Ling LI ,
  • Pu YANG ,
  • Liming LU ,
  • Buping LIU ,
  • Shengyong SU
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  • 1 Department of TCM preventive treatment of disease, the First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning 530022, China
    2 Guangxi University of Chinese Medicine, Nanning 530022, China
    3 Clinical Research and Big Data Laboratory, South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou 510006, China
    4 School of Public Health and Management, Guangzhou University of Chinese Medicine, Guangzhou 510006, China
    5 Department of Nutrition, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003, USA
    6 Department of acupuncture and moxibustion, the First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning 530022, China

Received date: 2024-11-29

  Accepted date: 2025-05-20

  Online published: 2026-01-28

Supported by

Guangxi Administration of Traditional Chinese Medicine High-Level Key Discipline in Traditional Chinese Medicine-Acupuncture and Moxibustion Project(2025013-03-05);Guangxi University of Chinese Medicine Guangxi School Apricot Grove Top Talents Project(2022C017)

Abstract

OBJECTIVE: To evaluate the effectiveness and safety of multiple acupuncture therapies in the treatment of allergic rhinitis (AR) using a network Meta-analysis.

METHODS: This network Meta-analysis adhered to the PRISMA-NMA guideline. Eight databases were systematically searched from inception to December 31, 2023, and retrieved references were managed using EndNote 20. The risk of bias in individual studies was assessed with the Cochrane RoB 2.0 tool (ROB 2.0). Data analysis was performed using R 4.2.1 and STATA 15.1.

RESULTS: A total of 56 studies that had enrolled 4859 patients with AR were included. Hand acupuncture (HA) combined with acupoint catgut embedding (AE), hand acupuncture with heat sensitive moxibustion (HA + HSM), and acupoint application were the most effective in attaining the clinical effective rate. HA + AE, hand acupuncture with indirect moxibustion (HA + IM), and electroacupuncture (EA) with AE ranked the highest with respect to the Rhinoconjunctivitis Quality of Life Questionnaire Score. HA + IM, HA, and HA + EA yielded the best Total Nasal Symptom Score, whereas HA + AE, EA + AE, and HA had the best results for the Total Non-Nasal Symptom Score. However, subgroup analyses of clinical efficacy revealed that HA + HSM had the best therapeutic effects in the short term, whereas HA + AE was the most effective in the medium to long term.

CONCLUSION: Combined acupuncture and moxibustion therapy may be a safe and effective intervention for patients with AR. HA + IM and HA + AE exhibited the most desirable therapeutic effects compared with other acupuncture and moxibustion therapies.

Cite this article

Lixia LIN , Xin LI , Ling LI , Pu YANG , Liming LU , Buping LIU , Shengyong SU . Multiple acupuncture and moxibustion therapies for allergic rhinitis in adults: a network Meta-analysis of randomized controlled trials[J]. Journal of Traditional Chinese Medicine, 2026 , 46(1) : 1 -13 . DOI: 10.19852/j.cnki.jtcm.2026.01.001

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