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Journal of Traditional Chinese Medicine >

2024 , Vol. 44 >Issue 4: 830 - 838

DOI: https://doi.org/10.19852/j.cnki.jtcm.20240515.006

Original articles

Acupuncture improves the live birth of patients with repeated implantation failure: a retrospective cohort study

  • Junjian SUN ,
  • Henghui XIE ,
  • Huanhuan LI ,
  • Xiangming TIAN ,
  • Yigong FANG ,
  • Wenhui ZHOU
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  • 1 Medical Center for Human Reproduction, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China
    2 Department of Gynecology, Beijing First Hospital of Integrated Chinese and Western Medicine, Beijing 100026, China
    3 Department of Acupuncture and Moxibustion, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China
    4 Medical Center for Human Reproduction, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China
    5 Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China

Received date: 2024-11-18

  Accepted date: 2024-03-14

  Online published: 2024-05-15

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Abstract

OBJECTIVE: To explore the therapeutic efficacy of acupuncture treatment on repeated implantation failure (RIF) patients with cryo-thawed embryo transfer (CET).

METHODS: In a retrospective cohort study, all eligible women undergoing RIF were recruited in our center from January 1, 2018 to December 31, 2021. The patients were grouped by whether an acceptance of acupuncture treatment before CET, including the acupuncture group (Acu-group, 55 cycles) and control group (Con-group, 244 cycles). Data were analyzed by using binary logistic regression to explore the relationship of acupuncture treatment with pregnancy outcomes.

RESULTS: The Acu-group had higher live-birth rate (LBR) [54.5% vs41.0%, respectively; odds ratio (OR) = 1.105, 95% confidence interval (CI) (1.029, 1.187), P =0.006] and ongoing pregnancy rate (OPR) [56.4% vs43.0%, respectively; OR= 1.100, 95% CI(1.025, 1.181), P =0.008] than the Con-group. There were no significant between-group differences in the rates of implantation [OR= 1.070, 95% CI(0.996, 1.149), P =0.064], clinical pregnancy [OR= 1.065, 95% CI(0.997, 1.138), P =0.061], biochemical pregnancy [OR= 1.002, 95% CI(0.903, 1.112), P =0.967], or miscarriage [OR= 0.778, 95% CI(0.551, 1.099), P =0.155]. Perinatal outcomes did not differ significantly between the two groups.

CONCLUSIONS: Acupuncture treatment could improve the LBR and OPR in RIF patients with CET cycles, suggesting a potential adjuvant therapy of acupuncture to improve the pregnancy outcomes in RIF patients.

Key words： acupuncture; repeated implantation failure; cryo-thawed embryo transfer; live birth rate

Cite this article

Junjian SUN , Henghui XIE , Huanhuan LI , Xiangming TIAN , Yigong FANG , Wenhui ZHOU . Acupuncture improves the live birth of patients with repeated implantation failure: a retrospective cohort study[J]. Journal of Traditional Chinese Medicine, 2024 , 44(4) : 830 -838 . DOI: 10.19852/j.cnki.jtcm.20240515.006

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