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Journal of Traditional Chinese Medicine >

2023 , Vol. 43 >Issue 4: 787 - 794

DOI: https://doi.org/10.19852/j.cnki.jtcm.20230524.001

Early intervention improves clinical responses to seasonal allergic rhinitis by stimulation in sphenopalatine ganglion (Xinwu acupoint)

  • Yuhao GUO ,
  • Liangran HUANG ,
  • Lei ZHANG ,
  • Wei YANG ,
  • Lixia HUANG ,
  • Wei LIU ,
  • Yuyan FAN
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  • 1 Department of Traditional Chinese Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
    2 Beijing Neurosurgical Institute, Beijing 100050, China
    3 Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
    4 Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
    5 Department of Traditional Chinese Medicine, Beijing Tongren Hospital, Beijing 100005, China

Received date: 2022-06-03

  Accepted date: 2022-10-14

  Online published: 2023-05-24

Supported by

National Natural Science Foundation of China: Study on the “Metabolic Memory” Effect of eNOS in Glomerular Endothelial Cells and the Role and Mechanism of Astragaloside IV in the Early Stages of Diabetic Nephropathy(81774214);Fundamental Research Funds of Chinese Medicine in Capital Medical University: Exploration of the Efficacy and Mechanism of Early Acupuncture Intervention in Seasonal Recurrent Rhinitis: a Randomized Clinical Study(16ZY03)

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Abstract

OBJECTIVE: To examine the efficacy of early intervention (4 weeks before pollen dispersal) with sphenopalatine ganglion (Xinwu acupoint) stimulation in patients with allergies after the onset of seasonal allergic rhinitis (SAR).

METHODS: This is a prospective, randomized and unblinded half-open study. Forty-one SAR volunteers were randomly assigned to either the sphenopalatine ganglion (SPG) acupuncture plus supplementary acupuncture (SPG group) or the sham-SPG acupuncture plus supplementary acupuncture (SA group) stimulation 4 weeks before the onset of allergy season. The changes of the total nasal symptom score (TNSS) and the Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) scores were measured on the first week in the onset of allergy season.

RESULTS: Four patients dropped out due to local hematoma and pain in the SPG and SA groups. The remaining 37 patients continued through to the end of the trial. After early intervention 4 weeks before the onset of allergy season, the sneezing, nasal congestion and itchiness scores in the first week of onset time were significantly lower in the SPG group than in the SA group patients (P < 0.001). The RQLQ score obtained at the onset of symptoms indicated that symptoms were more significantly ameliorated in the SPG group than in the SA group (P < 0.001).

CONCLUSIONS: The results of this study confirmed that early intervention by sphenopalatine ganglion (Xinwu acupoint) stimulation can effectively improve the symptoms and the quality of SAR patients’ daily lives.

Key words： rhinitis, allergic, seasonal; acupuncture; sphenopalatine; Xinwu acupoint; early intervention

Cite this article

Yuhao GUO , Liangran HUANG , Lei ZHANG , Wei YANG , Lixia HUANG , Wei LIU , Yuyan FAN . Early intervention improves clinical responses to seasonal allergic rhinitis by stimulation in sphenopalatine ganglion (Xinwu acupoint)[J]. Journal of Traditional Chinese Medicine, 2023 , 43(4) : 787 -794 . DOI: 10.19852/j.cnki.jtcm.20230524.001

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