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Journal of Traditional Chinese Medicine >

2023 , Vol. 43 >Issue 2: 359 - 364

DOI: https://doi.org/10.19852/j.cnki.jtcm.2023.02.007

Original articles

Clinical effect of acupuncture along fascia, meridians, and nerves combined with ultrasound-guided paravertebral nerve block in the treatment of postherpetic neuralgia: a randomized parallel-controlled study

  • Xiumei GAO ,
  • Chenyan WANG ,
  • Yong NI ,
  • Huiling ZHANG
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  • 1 Department of Anesthesiology, Xiyuan Hospital China Academy of Chinese Medical Science, Beijing 100091, China
    2 Pain Department, the Second Affiliated Hospital of Soochow University, Suzhou 215123, China
    3 Department of Pharmacology and Laboratory of Cerebrovascular Pharmacology, College of Pharmaceutical Science, Soochow University, Suzhou 215123, China

Received date: 2022-02-19

  Accepted date: 2022-05-27

  Online published: 2023-03-14

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Abstract

OBJECTIVE: To observe the clinical efficacy of acupuncture along fascia, meridians, and nerves combined with ultrasound-guided nerve blockage in the treatment of postherpetic neuralgia.

METHODS: A total of 61 outpatients with post-chest and back herpes zoster neuralgia were recruited in the Department of Pain at the Xiyuan Hospital, China Academy of Chinese Medical Sciences from May 2019 to June 2021. They were randomly divided into two groups. Thirty-one patients in the control group were treated with ultrasound-guided thoracic paravertebral nerve block (PVB) alone, one patient declined to continue during treatment (n = 30), and thirty patients in the observation group received the acupuncture along the fascia, meridians, and nerves combined with ultrasound-guided PVB treatment (n = 30). Both control and observation group received treatment weekly for 4 weeks. The medical history data such as age, sex, presence or absence of comorbidities and disease course were analyzed. The visual analog scale (VAS) score was used to assess the pain degree of two groups at T0 (before treatment), T1 (1-time treatment ended), T2 (2 times treatment ended), T3 (3 times treatment ended), and T4 (4 times treatment ended). The sleep state was examined by Pittsburgh Sleep Quality Index (PSQI) before and after the study.

RESULTS: There was no significant difference in general conditions between the control group and the observation group (P > 0.05). The VAS score in both control and observation group was decreased in a time-dependent manner after 1-4 weeks of treatment. There were no significant differences in VAS scores between the two groups after 1 or 2 weeks of treatment (P > 0.05). After 3 and 4 weeks of treatment, the VAS score was significantly decreased in the observation group compared with that in the control group (P < 0.001). In addition, the reduction in VAS score (after treatment-before treatment) between the two groups was statistically significant [D value: -1.53, 95% CI (-2.32, 0.74), P < 0.001]. Furthermore, the sleep state of patients in both groups markedly improved and much obvious in the observation group than that in the control group (P < 0.05).

CONCLUSION: These results suggest that a combination of acupuncture along fascia, meridians, and nerves with ultrasound-guided PVB treatment is more effective than ultrasound-guided PVB treatment alone.

Trial registration: Chinese Clinical Trial Registry ChiCTR2200057955.

Key words： neuralgia, postherpetic; visual analog scale; acupuncture along fascia, meridians and nerves; ultrasound-guided paravertebral nerve block

Cite this article

Xiumei GAO , Chenyan WANG , Yong NI , Huiling ZHANG . Clinical effect of acupuncture along fascia, meridians, and nerves combined with ultrasound-guided paravertebral nerve block in the treatment of postherpetic neuralgia: a randomized parallel-controlled study[J]. Journal of Traditional Chinese Medicine, 2023 , 43(2) : 359 -364 . DOI: 10.19852/j.cnki.jtcm.2023.02.007

References

1. Yu SY, Wan Y, Wan Q, et al. Consensus of Chinese experts on the diagnosis and treatment of postherpetic neuralgia. Zhong Guo Teng Tong Yi Xue Za Zhi 2016; 22: 161-7.
2. Wen XW, Li MZ. Advances in the study of the mechanisms and therapies of herpes zoster related pain. Neimenggu Zhong Yi Yao 2021; 1: 148-50.
3. Jiang QQ, Song YX, Jiang JT, Liu WB. Exploration of etiology and pathogenesis of herpes zoster in the elderly based on Traditional Chinese Medicine theory. Zhong Guo Yao Wu Jing Ji Xue 2012; 3: 375-7.
4. Avijgan M, Hajzargarbashi ST, Kamran A, Avijgan M. Postherpetic neuralgia: practical experiences return to Traditional Chinese Medicine. J Acupunct Meridian Stud 2017; 10: 157-64.
5. Wang ZJ, Liao YH, Zhao Y, et al. Clinical observation of ultrasound-guided thoracic foramen nerve block in the treatment of thoracolumbar postherpetic neuralgia. Zhong Guo Teng Tong Yi Xue Za Zhi 2020; 26: 863-70.
6. Zhen Q, Shen F, Tang SW, Xie SQ, Wang QL, Jiang WC. Clinical observation on skin plain needle for treatment of postherpetic neuralgia. Zhong Guo Zhong Yi Ji Chu Za Zhi 2020; 26: 1690-92.
7. He SS, Zhu JF, Jiang WJ, Ma J, Li GH, He YP. Sleep disturbance, negative affect and health-related quality of life in patients with maintenance hemodialysis. Psychol Health Med 2019; 24: 294-304.
8. Mallick-Searle T, Snodgrass B, Brant JM. Postherpetic neuralgia: epidemiology, pathophysiology, and pain management pharmacology. J Multidiscip Healthc 2016; 21: 447-54.
9. Jeon YH. Herpes zoster and postherpetic neuralgia: practical consideration for prevention and treatment. Korean J Pain 2015; 28: 177-84.
10. Doo AR, Choi JW, Lee JH, et al. The efficacy of selective nerve root block for the long-term outcome of postherpetic neuralgia. Korean J Pain 2019; 32: 215-22.
11. Fu ZJ, Wen B. Can postherpetic neuralgia be completely cured: a three-step treatment scheme for postherpetic neuralgia. Zhong Hua Teng Tong Xue Za Zhi 2021; 17: 115-7.
12. Lu LB, Xiong J, Chen ZJ, et al. Efficacy and safety of fire needle vs conventional acupuncture in the treatment of postherpetic neuralgia: a protocol for systematic review and Meta analysis. Medicine (Baltimore) 2020; 99: e22563.
13. Liu QY, Wu XL, Guo J, et al. Analgesic effect of electroacupuncture on postherpetic neuralgia: a trial protocol for a multicenter randomized controlled trial. Pain Ther 2021; 10: 1755-71.
14. Cui CB, Wang JJ, Wu ZC. On functional area of Back-shu based on relationship between Back-shu points and Jiaji points. Zhong Guo Zhen Jiu 2005; 25: 483-6.
15. Chen T, Zhang WW, Chu YX, et al. Acupuncture for pain management: molecular mechanisms of action. Am J Chin Med 2020; 48: 793-811.
16. Lyu Z, Guo Y, Gong Y, et al. The role of neuroglial crosstalk and synaptic plasticity-mediated central sensitization in acupuncture analgesia. Neural Plast 2021; 2021: 8881557.
17. Wu MS, Chen KH, Chen IF, et al. The efficacy of acupuncture in postoperative pain management: a systematic review and Meta-analysis. PLoS One 2016; 11: e0150367.
18. Bai Y, Wang J, Wu JP, et al. Review of evidence suggesting that the fascia network could be the anatomical basis for acupoints and meridians in the human body. Evid Based Complement Alternat Med 2011; 2011: 260510.
19. Liu F, Lu GJ, Bai ZY. Efficacy of repetitive paravertebral block combined with medication in the treatment of zoster-related pain with different courses. Neurosciences (Riyadh) 2021; 26: 192-8.
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