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Journal of Traditional Chinese Medicine >

2023 , Vol. 43 >Issue 1: 175 - 180

DOI: https://doi.org/10.19852/j.cnki.jtcm.20221006.002

Original articles

Effect and cerebral mechanism of moxibustion at heat-sensitized Yaoyangguan (GV3) in patients with lumbar disc herniation and myofascial pain syndrome by resting-state functionality magnetic resonance imaging: protocol for an observational study

  • Jun YANG ,
  • Jun XIONG ,
  • Shaozhong XU ,
  • Hongwu XIE ,
  • Jie XIANG
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  • 1 Jiangxi University of Chinese Medicine, Nanchang 330004, China
    2 Department of acupuncture and moxibustion, the Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang 330006, China
    3 Department of Radiology, the Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang 330006, China
XIONG Jun, Department of acupuncture and moxibustion, the Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang 330006, China; Jiangxi University of Chinese Medicine, Nanchang 330004, China. xiongjun196071@163.com. Telephone:+86-13970054277

Received date: 2021-12-11

  Accepted date: 2022-03-22

  Online published: 2023-01-10

Supported by

To Explore the Analgesic Mechanism of Brain Functional Network Regulation of moxibustion on Heat-sensitive Acupoints Based on rfMRI and MRS(20192ACB21007);Brain Functional Network Regulation and Neurobiochemical Mechanism of Heat-sensitive Moxibustion Analgesia(jxsq2019201104)

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Abstract

We want to explore the analgesic brain effect of the moxibustion at heat-sensitized Yaoyangguan (GV3) in patients with lumbar disc herniation (LDH) and myofascial pain syndrome (MPS). In an assessor-blinded observational study, we will include 15 LDH and 15 MPS. They will accept same treatment of heat-sensitive moxibustion at Yaoyangguan (GV3). The resting-state functionality magnetic resonance imaging image data of brain activities before and after treatment will be analyzed by mean fractional amplitude of low-frequency fluctuation, regional homogeneity analysis and brain functional connection. We select seed of first sensory cortex, second sensory cortex, insula cortex, periaqueductal gray and anterior cingulate cortex as the regions of interest to analyse the relationship between brain functional connectivity of pain-related networks and clinical data. Our study could disclose key brain targets and central response characteristics of the analgesic brain effect and the brain functional connection of heat-sensitive moxibustion.

Key words： lumbar disc herniation; myofascial pain syndrome; point GV3 (Yaoyangguan); resting-state functionality magnetic resonance imaging; heat-sensitive moxibustion; mean fractional amplitude of low-frequency fluctuation; regional homogeneity; pilot projects

Cite this article

Jun YANG , Jun XIONG , Shaozhong XU , Hongwu XIE , Jie XIANG . Effect and cerebral mechanism of moxibustion at heat-sensitized Yaoyangguan (GV3) in patients with lumbar disc herniation and myofascial pain syndrome by resting-state functionality magnetic resonance imaging: protocol for an observational study[J]. Journal of Traditional Chinese Medicine, 2023 , 43(1) : 175 -180 . DOI: 10.19852/j.cnki.jtcm.20221006.002

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