Original articles

Huoxue Jiedu Huayu recipe (活血解毒化瘀方) alleviates contralateral renal fibrosis in unilateral ureteral obstruction rats by inhibiting the transformation of macrophages to myofibroblast

  • Yunzhao XIONG ,
  • Lingjin LIU ,
  • Ziqian LIU ,
  • Gege CHEN ,
  • Juan HAO ,
  • Xiaomeng GAO ,
  • Panpan QIANG ,
  • Zheng WANG ,
  • Qingyou XU
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  • 1 Graduate School, Hebei University of Chinese Medicine; Hebei Key Laboratory of Integrative Medicine on Liver-Kidney Patterns, Hebei University of Chinese Medicine; Department of Internal Medicine, Hebei University of Chinese Medicine, Shijiazhuang 050091, China
    2 Graduate School, Hebei University of Chinese Medicine; Hebei Key Laboratory of Integrative Medicine on Liver-Kidney Patterns, Hebei University of Chinese Medicine, Shijiazhuang 050091, China
    3 Graduate School, Hebei University of Chinese Medicine; Hebei Key Laboratory of Integrative Medicine on Liver-Kidney Patterns, Hebei University of Chinese Medicine; Department of Internal Medicine, Hebei University of Chinese Medicine, Shijiazhuang 050091, China
Prof. WANG Zheng, Department of Internal Medicine, Hebei University of Chinese Medicine, Shijiazhuang 050091, China. 1017425887@qq.com. Telephone:+86-15350567700
Prof. XU Qingyou, Department of Internal Medicine, Hebei University of Chinese Medicine, Shijiazhuang 050091, China. qingyouxu@sohu.com;

Received date: 2022-05-18

  Accepted date: 2022-09-14

  Online published: 2023-01-10

Supported by

Effect of Macrophage-to-Myofibroblast Transition in Contralateral Kidney of Unilateral Ureteral Obstruction Rats Through the Aldosterone/ MR/SGK1 Pathway and Inhibition of Chinese Herbs(81873251);Aldosterone-induced Macrophage Polarization-lymphatic Endothelial Cell-like Trans-formation Involved in Renal Fibrosis and the Protective Effect of Yiqi Jiedu Huayu Herbs(82205006);Mechanism of Renal Fibrosis Induced by NF-kB/IL-8 Induced MMT in UUO Rats(BJK2022004)

Cite this article

Yunzhao XIONG , Lingjin LIU , Ziqian LIU , Gege CHEN , Juan HAO , Xiaomeng GAO , Panpan QIANG , Zheng WANG , Qingyou XU . Huoxue Jiedu Huayu recipe (活血解毒化瘀方) alleviates contralateral renal fibrosis in unilateral ureteral obstruction rats by inhibiting the transformation of macrophages to myofibroblast[J]. Journal of Traditional Chinese Medicine, 2023 , 43(1) : 105 -112 . DOI: 10.19852/j.cnki.jtcm.2023.01.009

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