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Journal of Traditional Chinese Medicine >

2022 , Vol. 42 >Issue 6: 972 - 979

DOI: https://doi.org/10.19852/j.cnki.jtcm.2022.06.008

Research Articles

Efficacy of stimulating Mingmen (GV4) and Guanyuan (CV4) on kidney Yang deficiency in rat model: laser irradiation vs traditional moxibustion

  • Jing FANG ,
  • Wen PAN ,
  • Xiangyun WANG ,
  • Fengxing LI ,
  • Ling ZHAO ,
  • Zouqin HUANG ,
  • Xueyong SHEN
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  • 1 Acupuncture and Tuina School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
    2 Acupuncture and Tuina School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; Shanghai Research Center of Acupuncture & Meridian, Shanghai 201203, China
    3 Department of Acupuncture,Shanghai Pudong New District Hospital of Traditional Chinese Medicine, Shanghai 201203, China
HUANG Zouqin, Department of Acupuncture, Shanghai Pudong New District Hospital of Traditional Chinese Medicine, Shanghai 201203, China. hzqmusic@yeah.net,Telephone: +86-13917674196; +86-13564599607
ZHAO Ling, Acupuncture and Tuina School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. zl2@shutcm.edu.cn;

Received date: 2021-09-12

  Accepted date: 2021-12-02

  Online published: 2022-11-01

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Abstract

OBJECTIVE: To investigate the effect of 10.6-μm laser moxibustion (LM) and traditional moxibustion (TM) on kidney Yang deficiency (KYD) model rats.

METHODS: Forty rats were randomly divided into normal, model, 10.6-μm LM, and TM groups. KYD was induced through intramuscular hydrocortisone injections.

RESULTS: Hydrocortisone injections decreased the body weight, activity, and temperature and induced changes in the organ coefficients. Compared with the model group, TM and LM treatment prevented body weight loss and improved organ coefficients after treatment (P < 0.05), while the body weight remained lower compared to the normal group (P < 0.01). Additionally, LM and TM significantly increased the levels of urine 17-hydroxycorticosteroid (17-OHCS) compared with the model group (P < 0.01). The LM and TM groups showed a greater distance travelled across the central area, time spent in the central area, and 5-min total distance than the model group in the open field test (P < 0.01). The model group had the lowest anal or surface temperature (P < 0.05); there were no differences among the other three groups (P > 0.05). TM treatment increased the temperature of Mingmen (GV4) and Guanyuan (CV4) compared to the model group (P < 0.05, P < 0.01). LM treatment increased Mingmen (GV4) temperature (P < 0.05), while there were no obvious differences in Guanyuan (CV4) temperature compared with the normal group before and after treatment (P > 0.05). There was a positive correlation between Mingmen (GV4)/Guanyuan (CV4) temperature and 17-OHCS levels.

CONCLUSIONS: LM and TM treatment can improve KYD symptoms, and acupoint temperature changes may be an objective indicator of KYD.

Key words： hydrocortisone; temperature; acupoints; micro-circulation; Kidney-Yang deficiency; laser moxibustion

Cite this article

Jing FANG , Wen PAN , Xiangyun WANG , Fengxing LI , Ling ZHAO , Zouqin HUANG , Xueyong SHEN . Efficacy of stimulating Mingmen (GV4) and Guanyuan (CV4) on kidney Yang deficiency in rat model: laser irradiation vs traditional moxibustion[J]. Journal of Traditional Chinese Medicine, 2022 , 42(6) : 972 -979 . DOI: 10.19852/j.cnki.jtcm.2022.06.008

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