Recurrence quantification analysis on pulse morphological changes in patients with coronary heart disease

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  • Laboratory of Synthetic Study on TCM Diagnostic Information,Shanghai University of Traditional Chinese Medicine;Center for Mechatronics Engineering,East China University of Science and Technology;

Accepted date: 2012-12-15

  Online published: 2012-12-15

Abstract

OBJECTIVE:To show that the pulse diagnosis used in Traditional Chinese Medicine,combined with nonlinear dynamic analysis,can help identify cardiovascular diseases.METHODS:Recurrence quantification analysis(RQA) was used to study pulse morphological changes in 37 inpatients with coronary heart disease(CHD) and 37 normal subjects(controls).An independent sample t-test detected significant differences in RQA measures of their pulses.A support vector machine(SVM) classified the groups according to their RQA measures.Classic time-domain parameters were used for comparison.RESULTS:RQA measures can be divided into two groups.One group of measures [ecurrence rate(RR),determinism(DEL),average diagonal line length(L),maximum length of diagonal structures(Lmax),Shannon entropy of the frequency distribution of diagonal line lengths(ENTR),laminarity(LAM),average length of vertical structures(TT),maximum length of vertical structures(Vmax)] showed significantly higher values for patients with CHD than for normal subjects(P

Cite this article

Rui Guo, Yiqin Wang, Jianjun Yan, Hanxia Yan . Recurrence quantification analysis on pulse morphological changes in patients with coronary heart disease[J]. Journal of Traditional Chinese Medicine, 2012 , 32(04) : 571 -577 . DOI: 10.1016/s0254-6272(13)60073-4

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