OBJECTIVE:To evaluate the clinical efficacy and safety of external application of Traditional Chinese Medicine(EATCM)on acute gouty arthritis(AGA).METHODS:Six electronic data bases were retrieved from their inception to march 2017.15 randomized controlled clinical trials(RCTs)were included.The quality of the literatures was assessed according to Cochrane review criteria by using RevMan5.3 software;and related data was counted using Stata14.0 software.RESULTS:There was no significant difference in C-reactiveprotein(CRP)between experimental intervention group and control group[(WMD= 1.093,95% CI(-2.514,4.701);P=0.553)].In terms of overall efficacy,the EATCM's treatment group was significantly superior to control group[(OR = 3.692; 95% CI(2.408,5.661); P