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Journal of Traditional Chinese Medicine ›› 2013, Vol. 33 ›› Issue (05): 603-607.DOI: 10.1016/s0254-6272(14)60028-5

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Effectiveness of external Sanjierupi Gao on mastalgia caused by mammary gland hyperplasia: a placebo controlled trial

Yingyi Fan, Xiaohua Pei, Zhaolan Liu, Zhongyuan Xia, Dongxiao Zhang, Afeng Song, Duo Liu   

  1. Surgical Department of the Third Hospital Affiliated to Beijing University of Traditional Chinese Medicine;Centre for Evidence-based Chinese Medicine,Beijing University of Chinese Medicine;Surgical Department of TCM in Sino-Japanese Friendship Hospital;Mammary Department of Dongfang Hospital under Beijing University of Traditional Chinese Medicine;Surgical Department of the First Hospital Affiliated to Tianjin University of Traditional Chinese Medicine;Surgical Department of Hubei Provincial Hospital of Traditional Chinese Medicine;
  • Accepted:2013-10-15 Online:2013-10-15 Published:2013-10-15

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Abstract: OBJECTIVE:To evaluate the curative effect of external application of the Chinese drug,Sanjierupi Gao,on mastalgia caused by mammary gland hyperplasia.METHODS:This randomized,double-blinded,and placebo controlled study enrolled 260 patients with mammary gland hyperplasia from five hospitals.Patients were randomly and equally divided in-to a Sanjierupi Gao treatment group and a placebo control group.An adhesive plaster was applied to the most painful area on either breast for 7 h a day.Treatment lasted for two menstrual cycles without application during menstruation.Mastalgia was used as the main index of curative effect.The change before and after treatment in days of mastalgia,the time to alleviate pain,pain extent,and severe pain scores were observed.RESULTS:Compared to the control group,the treatment group had significantly fewer days of mastalgia(P

Key words: Fibrocystic disease of breast, Pain, Treatment outcome, Application therapy

Cite this article

Yingyi Fan, Xiaohua Pei, Zhaolan Liu, Zhongyuan Xia, Dongxiao Zhang, Afeng Song, Duo Liu. Effectiveness of external Sanjierupi Gao on mastalgia caused by mammary gland hyperplasia: a placebo controlled trial[J]. Journal of Traditional Chinese Medicine, 2013, 33(05): 603-607.