Journal of Traditional Chinese Medicine ›› 2012, Vol. 32 ›› Issue (04): 571-577.DOI: 10.1016/s0254-6272(13)60073-4

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Recurrence quantification analysis on pulse morphological changes in patients with coronary heart disease

Rui Guo, Yiqin Wang, Jianjun Yan, Hanxia Yan   

  1. Laboratory of Synthetic Study on TCM Diagnostic Information,Shanghai University of Traditional Chinese Medicine;Center for Mechatronics Engineering,East China University of Science and Technology;
  • Accepted:2012-12-15 Online:2012-12-15 Published:2012-12-15

Abstract: OBJECTIVE:To show that the pulse diagnosis used in Traditional Chinese Medicine,combined with nonlinear dynamic analysis,can help identify cardiovascular diseases.METHODS:Recurrence quantification analysis(RQA) was used to study pulse morphological changes in 37 inpatients with coronary heart disease(CHD) and 37 normal subjects(controls).An independent sample t-test detected significant differences in RQA measures of their pulses.A support vector machine(SVM) classified the groups according to their RQA measures.Classic time-domain parameters were used for comparison.RESULTS:RQA measures can be divided into two groups.One group of measures [ecurrence rate(RR),determinism(DEL),average diagonal line length(L),maximum length of diagonal structures(Lmax),Shannon entropy of the frequency distribution of diagonal line lengths(ENTR),laminarity(LAM),average length of vertical structures(TT),maximum length of vertical structures(Vmax)] showed significantly higher values for patients with CHD than for normal subjects(P

Key words: Pulse-taking, Cardiovascular diseases, Recurrence quantification analysis

Cite this article

Rui Guo, Yiqin Wang, Jianjun Yan, Hanxia Yan. Recurrence quantification analysis on pulse morphological changes in patients with coronary heart disease[J]. Journal of Traditional Chinese Medicine, 2012, 32(04): 571-577.