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Journal of Traditional Chinese Medicine ›› 2012, Vol. 32 ›› Issue (04): 554-560.DOI: 10.1016/s0254-6272(13)60070-9

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Randomized controlled multicenter clinical trial for integrated treatment of community-acquired pneumonia based on Traditional Chinese Medicine syndrome differentiation

Jiansheng Li, Xueqing Yu, Suyun Li, Haifeng Wang, Yunping Bai, Minghang Wang, Zikai Sun, Wei Zhang, Zhaoshan Zhou, Xianhua Jia, Qingwei Zhou   

  1. Department of Respiratory Medicine,The First Affiliated Hospital of Henan College of Traditional Chinese Medicine;the Geriatric Institute of Henan University of TCM;Department of Respiratory Medicine,The First Affiliated Hospital of Henan University of Traditional Chinese Medicine;Jiangsu Provincial Hospital of TCM;The Affiliated Hospital of Shandong University of TCM;Qingdao Hospital of TCM;
  • Accepted:2012-12-15 Online:2012-12-15 Published:2012-12-15

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Abstract: OBJECTIVE:To evaluate the efficacy and safety of treatment based on syndrome differentiation ofTraditional Chinese Medicine(TCM) for community-acquired pneumonia(CAP).METHODS:A total of 240 CAP patients were randomly divided into the following two groups:thecontrol group was treated by anti-infection plus conventional medicine treatment;and the trial group was treated by TCM plus the above-mentioned treatment given to the controls.The course of treatment was 14 days,and the patients were followed up for 7 days.RESULTS:Of the 240 patients,235 accomplished the whole process of treatment.The five patients who withdrew from the study were brought into an intent-to-treat analysis.The therapeutic effects of the trial group were superior to those of the control group(P0.05),white blood cell count(P>0.05),bacterial clearance rate(P>0.05),and adverse reactions between the two integrated groups.CONCLUSION:Treatment based on TCM syndrome differentiation for CAP has the advantages of resulting in less time to achieve a stable clinical condition,improvement of clinical symptoms and quality of life,and is comparatively safe.

Key words: Community-acquired infections, Pneumonia, Syndrome differentiation treatment, Randomized controlled trials

Cite this article

Jiansheng Li, Xueqing Yu, Suyun Li, Haifeng Wang, Yunping Bai, Minghang Wang, Zikai Sun, Wei Zhang, Zhaoshan Zhou, Xianhua Jia, Qingwei Zhou. Randomized controlled multicenter clinical trial for integrated treatment of community-acquired pneumonia based on Traditional Chinese Medicine syndrome differentiation[J]. Journal of Traditional Chinese Medicine, 2012, 32(04): 554-560.