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Journal of Traditional Chinese Medicine ›› 2012, Vol. 32 ›› Issue (01): 58-62.DOI: 10.1016/s0254-6272(12)60032-6

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Effect of houttuynia cordata aetherolea on adiponectin and connective tissue growth factor in a rat model of diabetes mellitus

Wang Hai Ying , Bao Jun Lu   

  1. Shanghai University of Tradi tional Chinese Medicine;
  • Accepted:2012-03-15 Online:2012-03-15 Published:2012-03-15

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Abstract: OBJECTIVE:To determine the effect of Houttuynia cordata Aetherolea on connective tissue growth factor and adiponectin in a rat model of diabetes mellitus(DM).METHODS:DM was induced in rats using streptozotocin(STZ) and high glucose-lipid animal feed.Animals were then treated with Houttuynia cordata Aetherolea for 8 weeks.Changes in connective tissue growth factor and adiponectin levels in rats were observed.RESULTS:Connective tissue growth factor and adiponectin levels in rats with DM improved after Houttuynia cordata Aetherolea treatment.CONCLUSION:Houttuynia cordata Aetherolea had a positive effect on rats with DM by reducing levels of connective tissue growth factor and increasing adiponectin levels.

Key words: Diabetes mellitus, Houttuynia cordata, Connective Tissue Growth factor(CTGF), Adiponectin

Cite this article

Wang Hai Ying , Bao Jun Lu. Effect of houttuynia cordata aetherolea on adiponectin and connective tissue growth factor in a rat model of diabetes mellitus[J]. Journal of Traditional Chinese Medicine, 2012, 32(01): 58-62.