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Journal of Traditional Chinese Medicine ›› 2014, Vol. 34 ›› Issue (06): 652-656.DOI: 10.1016/S0254-6272(15)30078-9

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Clinical treatment of depressive patients with Anshendingzhi decoction

Jianyu Yang, Lijuan Jiang, Yang Li, Qingwen Zhu, Dong Liu, Wugeng Xue, Bolong Cao, Yingke Liu, Xing Wang   

  1. National Prominent Chinese Medicine Guangrong Sun Inheritance Studio, Beijing University of Chinese Medicine;The Prominent Chinese Medicine Doctors' Studio, Beijing Hepingli Hospital;Department of Science and Education, Yunnan Provincial Hospital of Traditional Chinese Medicine;Preclinical School of Beijing University of Chinese Medicine;School of Basic Medical, Beijing Fangzhuang Communuty Health Service Center;Department of Endocrinology, Eastern Area of Dongzhimen Hospital, Beijing University of Chinese Medicine;Department of Traditional Chinese Medicine,Beijing Tongrentang Hospital of Traditional Chinese Medicine;
  • Accepted:2014-12-15 Online:2014-12-15 Published:2022-04-05

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Abstract: OBJECTIVE: To determine the effects of Anshendingzhi decoction(ASDZD) on depression, to com-pare ASDZD with Danzhixiaoyao pill(DZXYP), and to provide evidence for the clinical treatment of depression with Traditional Chinese Medicine.METHODS: Seventy-eight patients with depression were enrolled from 2011 to 2013 in this double-blinded study. Patients were randomly divided into two groups: ASDZD(treatment group, n=39)and DZXYP(control group, n=39). Hamilton Depressive Scale and TCM Syndrome Differentiation Scale were used to assess depression and efficacy before treatment and 2, 4, and 6 weeks after treatment.The Treatment Emergent Symptoms Scale(TESS)was used to evaluate adverse reactions, observe,and record treatment outcomes.RESULTS: ASDZD was significantly more effective than DZXYP. There were significant differences between the two groups in terms of recovered patients, overall response rate, and TESS score(all P

Key words: Depression, Anshendizhi decoction, Danzhixiaoyao pill

Cite this article

Jianyu Yang, Lijuan Jiang, Yang Li, Qingwen Zhu, Dong Liu, Wugeng Xue, Bolong Cao, Yingke Liu, Xing Wang. Clinical treatment of depressive patients with Anshendingzhi decoction[J]. Journal of Traditional Chinese Medicine, 2014, 34(06): 652-656.