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Journal of Traditional Chinese Medicine ›› 2019, Vol. 39 ›› Issue (02): 207-212.DOI: 10.19852/j.cnki.jtcm.2019.02.008

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Twelve-week study of moxa smoke: occupational exposure in female rats

Han Li, Huang Chang, Yang Jia, Wang Lei, Bai Hua, Liu Juntian, Jian Huang, Liu Ping, Lim MinYee, Ju Dahong, Lao Lixing, Liu Changxi, Zhao Baixiao, Sun Wen, Xu Anping, Yang Xiuyan, Zhang Cong, He Rui   

  1. Shool of Chinese medicine, Beijing University of Chinese Medicine;Shool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine;Department of Acupunture, Beijing Dong Fang Hospital;Healthcare Management Center, Beijing Electric Power Hospital;Medical Experimental Center, China Academy of Chinese Medical Sciences;School of Chinese Medicine, The University of Hong Kong;
  • Online:2019-04-15 Published:2019-04-15
  • Supported by:
    Supported by National Natural Science Foundation of China:Effect of Moxibustion on"Longevity Gene"SIRT1 Regulation in Aged Mice(No.81403449), Effect of Moxibustion and its Therapeutic Factors on Mitochondrial Energy Metabolism and Apotosis Pathyway in APP/PS1 Transgenic Alzheimer's Disease Mouse Model(No.81574068), Project of Beijing University of Chinese Medicine(2018-JYBZZ-JS009), National Program on Key Basic Research Project(973 Program):the Study of Components and Mecha-nisms of Artemisia and the Product and Moxibustion and Safety Evaluation(No.2009CB522906)

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Abstract: OBJECTIVE: To assess the toxicity of moxa smoke in rats.METHODS: Forty-eight female Wister rats were randomly divided into 4 groups(n = 12/group) to simulate moxa smoke exposure in Chinese medicine clinics(CMCs): the control group, and three moxa-smoke exposed groups of PM10 mass concentrations 3-5, 7-9 and 27-30 mg/m~3, respectively.These concentrations were 1 ×, 2-3 ×, and 7-9 ×fold the concentrations found in CMCs. Exposures continued for 12 weeks(200 min/d, 5 d/week).RESULTS: No deaths were noted. After the exposure, the body weights, ratios of organ weight to body weight, urinary parameters, hematological parameters, clinical chemistry parameters and microscopic examinations revealed no obvious toxicity.CONCLUSION: Moxa smoke did not induce toxic effects in female rats in the study. These findings provide new evidence to the toxicity of moxa smoke.

Key words: Moxibustion, Artemisia, Smoking,non-tobacco products, Toxicity tests

Cite this article

Han Li, Huang Chang, Yang Jia, Wang Lei, Bai Hua, Liu Juntian, Jian Huang, Liu Ping, Lim MinYee, Ju Dahong, Lao Lixing, Liu Changxi, Zhao Baixiao, Sun Wen, Xu Anping, Yang Xiuyan, Zhang Cong, He Rui. Twelve-week study of moxa smoke: occupational exposure in female rats[J]. Journal of Traditional Chinese Medicine, 2019, 39(02): 207-212.