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Journal of Traditional Chinese Medicine ›› 2013, Vol. 33 ›› Issue (03): 413-416.DOI: 10.1016/s0254-6272(13)60189-2

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Pharmacological effects of Astragaloside IV: a literature review

Shuang Ren, Hua Zhang, Yongping Mu, Mingyu Sun, Ping Liu   

  1. Key Laboratory of Liver and Kidney Diseases, Institute of Liver Diseases, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine;E-institute of TCM Internal Medicine, Shanghai Municipal Education Commission, Shanghai University of TCM;
  • Accepted:2013-06-15 Online:2013-06-15 Published:2013-06-15

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Abstract: OBJECTIVE: To review the pharmacological effects and mechanisms of action of Astragaloside IV in Huangqi (Radix Astragali Mongolici). METHODS: Aticles focusing on Astragaloside IV in English and Chinese in databases were collected and reviewed in order to summarize the latest extraction separation, pharmacokinetics, and the pharmacological effects of astrageloside IV. RESULTS: Protective effects of Astrageloside IV on the cardiovascular system, immune, digestive, nervous system were identified, and the action mechanisms were associated with regulation of the calcium balance, anti-oxydant, antiapoptosis, antivirus, and so on. CONCLUSION: Astrageloside IV has broad application prospects, especially in cardiovascular diseases, digestive diseases, cancer and other modern high incidence, high-risk diseases, and could be developed as a medicine.

Key words: Astragaloside IV, Extraction, Pharmaco- kinetics, Pharmacology

Cite this article

Shuang Ren, Hua Zhang, Yongping Mu, Mingyu Sun, Ping Liu. Pharmacological effects of Astragaloside IV: a literature review[J]. Journal of Traditional Chinese Medicine, 2013, 33(03): 413-416.