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Journal of Traditional Chinese Medicine ›› 2013, Vol. 33 ›› Issue (02): 250-252.DOI: 10.1016/s0254-6272(13)60134-x

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Effect of Linguizhugan decoction on hyperlipidemia rats with intermittent fasting

Yubin Yang, Jian Qin, Bin Ke, Junjie Zhang, Lanying Shi, Qiong Li   

  1. Traditional Chinese Medicine Department,First Affiliated Hospital of Sun Yat-Sen University;
  • Accepted:2013-04-15 Online:2013-04-15 Published:2013-04-15

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Abstract: OBJECTIVE:To explore the effect of Linguizhugan decoction on hyperlipidemia rats with caloric restriction.METHODS:The hyperlipidemia model of rat was induced by high fat diet for 8 weeks.After the model was established,26 rats were randomly divided into 4 groups:the control group(n=6),the model group(n=6),the intermittent fasting(IF) group(n= 8),and the IF and herbal medicine(IFH) group(n= 6).IF group was applied intermittent fasting every other day.The IFH group was given Linguizhugan decoction every day and intermittent fasting every other day.Blood samples were taken at the end of 16 weeks,and serum ghrelin and lipid was tested.RESULTS:Serum ghrelin in the IF group significantly increased(P

Key words: Hyperlipidemias, Fasting, Ghrelin, Linguizhugan decoction

Cite this article

Yubin Yang, Jian Qin, Bin Ke, Junjie Zhang, Lanying Shi, Qiong Li. Effect of Linguizhugan decoction on hyperlipidemia rats with intermittent fasting[J]. Journal of Traditional Chinese Medicine, 2013, 33(02): 250-252.