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Journal of Traditional Chinese Medicine ›› 2012, Vol. 32 ›› Issue (02): 193-198.DOI: 10.1016/s0254-6272(13)60010-2

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Protective effects of Modified Linggui Zhugan Decoction combined with short-term very low calorie diets on cardiovascular risk factors in obese patients with impaired glucose tolerance

Ke Bin , Shi Lin , Zhang Jun Jie , Chen Ding Sheng , Meng Jun , Qin Jian   

  1. Traditional Chinese Medicine Department,First Affiliated Hospital of Sun Yat-Sen University;Traditional Chinese Medicine Department,Zhu Jiang Hospital of Southern Medical University;
  • Accepted:2012-06-15 Online:2012-06-15 Published:2012-06-15

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Abstract: OBJECTIVE:To observe the protective effects of modified Linggui Zhugan Decoction combined with short-term very low calorie diets(VLCDs) on cardiovascular risk factors in obese patients with impaired glucose tolerance(IGT).METHODS:Eighty-five obese patients with IGT of spleen hypofunction and dampness accumulation type were randomly divided into treated group(n=45)and control group(n=40).The treated group was given Linggui Zhugan Decoction combined short-term VLCDs.The control group was given basic weight-reduction treatment.The total course was 6 months.Changes of fasting plasma glucose(FPG),2-hour postprandial blood glucose(2hPG),glycosylated hemoglobin(HbA1c),fasting insulin(FINS),lipid metabolism,blood pressure,body mass index(BMI) and waist circumference(WC) were observed,and the outcomes were reviewed after the treatment.RESULTS:Compared with the control group,the levels of FPG,2hPG,HbA1c,FINS,HOMA-IR decreased significantly(P

Key words: Linggui Zhugan Decoction, Very Low Calorie Diets, Impaired Glucose Tolerance, Obesity

Cite this article

Ke Bin , Shi Lin , Zhang Jun Jie , Chen Ding Sheng , Meng Jun , Qin Jian. Protective effects of Modified Linggui Zhugan Decoction combined with short-term very low calorie diets on cardiovascular risk factors in obese patients with impaired glucose tolerance[J]. Journal of Traditional Chinese Medicine, 2012, 32(02): 193-198.