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Journal of Traditional Chinese Medicine ›› 2012, Vol. 32 ›› Issue (01): 1-5.DOI: 10.1016/s0254-6272(12)60023-5

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Integrated traditional and Western medicine for treatment of depression based on syndrome differentiation:a meta-analysis of randomized controlled trials based on the Hamilton depression scale

Kou Mei Jing , Chen Jia Xu   

  1. School of Pre-clinical Medicine,Beijing University of Chinese Medicine;Hubei University of Chinese Medicine;
  • Accepted:2012-03-15 Online:2012-03-15 Published:2012-03-15

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Abstract: OBJECTIVE:To systematically review the benefits of integrated traditional and Western medicine therapies based on the Hamilton depression scale(HAMD) following syndrome differentiation of depression.METHODS:We searched six English and Chinese electronic databases for randomized clinical trials(RCTs) on integrated traditional and Western medicine for treatment of depression.Two authors extracted data and independently assessed the trial quality.RevMan 5 software was used for data analyses with an effect estimate presented as weighted mean difference(WMD) with a 95% confidence interval(CI).RESULTS:Seven RCTs with 576 participants were identified for this review.All trials were eligible for the meta-analysis and were evaluated as unclear or having a risk of bias.Meta-analysis showed,compared with Western medicine alone,integrated traditional and Western medicine based on syndrome differentiation could improve the effect of treatment represented by the HAMD [WMD=-2.39,CI(-2.96,-1.83),Z=8.29,P

Key words: Syndrome differentiation, Depression, Integrated traditional and western medicine, Meta-analysis, Randomized controlled trials

Cite this article

Kou Mei Jing , Chen Jia Xu. Integrated traditional and Western medicine for treatment of depression based on syndrome differentiation:a meta-analysis of randomized controlled trials based on the Hamilton depression scale[J]. Journal of Traditional Chinese Medicine, 2012, 32(01): 1-5.